2158, SDI warn about potential danger of Tiberium and Council rather didn't mess with it, Council only respond with cold reply.

Biotic implants from Citadel was created and further research was accelerated

2159, Human discover that Tiberium is chemically dangerous to Element Zero

2160, SDI parliament formed on Arcturus Station

Paris and Charon frigate class was entering service

2161, SDI decide to quarantine Forgotten on planet Tratos under Kane policy

Ion drive modifying Mass effect drive, effectively made efficiency for increasing human ship size more than any races

2162, Arcturus Station construction was completed

Reach on Epsilon Eridani was colonized

2163, L1 biotic implants used by SDI, AI Apollyon was created based on Nod scientist

SPARTAN IV program derived

2164, Ivor Johnstagg sentenced 21 years for attempt murder Volus ambassador, Venta Tox and jeopardize Human-Council relationship

2165, SDI and Citadel agree to form the Citadel Compromise which bear 7 fruits about human role in Citadel Space, and SDI embassy establishment those were:

1. Unshackled AI EVA was permitted on human worlds and all space under human jurisdiction but banned to enter Citadel Space

2. SDI and humanity permitted to open any dormant relay which 100 light years from Citadel Border and hostile race unleashed by such actions was total responsible to SDI

3. Liquid Tiberium Bomb arsenal was limited up only 700 warheads for preservation of peace and existence. Ion canon and Nuclear warhead number was not limited

4. Treaty of Farixen was disregarded by SDI at all

5. Human contribute 30 vessels to Citadel Fleet for peace preservation and mutual coexistence (Without Tiberium arsenal)

6. Citadel wouldn't make attempt to study Tiberium for prevent the cataclysm

7. Genetic Engineering was allowed under appropriate procedure and medical purpose

2166, SDI ban Tiberium sharing after insist that they won't handle destructive substance to any alien

2167, Ion Canon Gen .V enter service

2170, Orbital Drop Shock Trooper begin full service and revealed to public

2171, Batarian closed their embassy on Citadel in protest to special treatment for human colonization over Skyllian Verge and isolating themselves from rest of galaxy as they gradually become rogue.

2172, Discovery of Travelyan shield world by SDI, numerous Mjolnir armor variants are developed in here

2173, Humanity discover existence of Requiem and its Promethean Knights based on data in Travelyan. Planet was quarantined and record of its existence was erased as search for Forerunner artifact continue under bloodshed with Promethean. Still, Ur Didact didn't awaken

2174, biggest human ship ISV Everest constructed with 2,3 km length, only ship in galaxy rivaling Destiny Ascension

2175, Mars population reaching 340 millions

2176, Batarian raid human colony, Elysium and kill or enslave the colonist

Jon Grissom Academy was commissioned over Vetus for upgrading Gagarin station function

2177, Akuze detect that Thrasher Maws are mutated with Tiberium, attempt to quarantine it was successful at cost 180 humans

2178, Battle of Torfan, Torfan was destroyed with Nuclear bomb and Batarian retreat to their own space

2179, Reach population reach 700 million

2183, The Great War: Battle of Eden Prime, Geth assault on Eden Prime repelled. Battle of Feros, Human fight Thorian, Battle of Noveria, Human quarantine the revived rachni, battle of Virmire, Human neutralize Krogan breeding facility, Battle of Citadel, Sovereign was destroyed during assault of Citadel, Battle of Terra Nova, Batarian de-orbiting asteroid attempt was prevented.

Human gaining Council seat, Anderson serves as human face

2185, Collector posing threat to Terminus colonies by abducting and processing them on Collector Base beyond dangerous Omega 4 relay, they kill Commander Shepard in process but Illusive Man initiate Lazarus project and resurrect Shepard, reconstructing Normandy and assemble task force to stop the Collectors. Collector was declared extinct and base left intact seized by Cerberus.

Desolation of Arathoht, for sake of galaxy, Bahak system destroyed after asteroid Golgotha crashed on Alpha relay thus obliterating Arathoht and its 300.000 residents

2186, 1 May, Covenant invade Elysium and trigger third contact war, on 20 may peace later negotiated

Detonation of Liquid Tiberium Bomb, Return of the Scrin, in midst of Illium, Scrin return from many shelter worlds in uncharted cluster in Terminus Systems, later contact with other colonies was lost. Councilor made attempt to persuade human to control the threats. SDI respond by send fourth fleet and result was severe devastation majority of the fleet. Now, Spectre Shepard, represent SDI and humanity was made attempt to gather many fleets as much as possible to destroy the Scrin. Reaper, on dark space realizing that cycles must continue. on 18 October, Reaper invade Vular system, Reaper war begin.