It was yet another ordinary day in Honnoji Academy. Ryuko Matoi was going up to the academy as usual, and then suddenly she began feeling like she doesn't remember a lot. Within an hour, she passed out.

When she finally woke up, she realizes that she's in a cold room with a "Super Mario Bros." poster on the wall. Ryuko tried very hard to find out what was going on, but then she found a paper on the desk. "Please meet at the gym... oh, crap, I'm late!", she said, as she rushed out the door.

Upon arriving at the gym, 15 others were there, including Satsuki Kiriyuin, Mako Mankanshoku, and the Student Council's Elite Four, who, like Ryuko, have also had their memories wiped clean. "Who the hell do you think we are?", asked Nonon. Ryuko said, "Part of the Elite Four. But hey, if Satsuki's trapped here too, then who's running this damn place?" "I dunno", said Mako, out of innocence. Uzu Sanageyama said, "Well, if we're going to see what this thing is, we'll just have to wait, shall we?" Nui Harime responded, "So when is the guy running the place supposed to be here?"

Suddenly, Monokuma sprang up and greeted everyone. "Why, this is quite a crowd, is it?", said Monokuma. Ryuko said, "Yeah. Hard to please this crowd, is it?" Monokuma said, "What? You say that I can't please an entire group at once? Well, how about this? We'll see how it will go. I've got an idea. How about good old-fashioned murder?" Everyone suddenly became shocked. Ryuko said, "Wait... you said murder?" Monokuma replied, "Correct! There is only one truth- the student who commits murder- and gets away with it- will be free to leave and graduate. Any questions?" Nonon said, "You forgot to add that we're probably going to stay here for the rest of our natural lives." Monokuma replied, "Oh, yeah. That part. All of you should know that by now." Ryuko said, "So you're probably going to convince us to kill each other? That doesn't seem right." Monokuma said, "I don't directly kill anyone, you know." Ryuko said, "I don't see how you can get away with the whole damn thing." Monokuma responded, "Do I look like a guy who can send villains flying with one punch? I don't think so." Nonon replied, "Well, I don't look like I come from Palm Town." Monokuma replied, "Give Nonon a medal." Ira replied, "You won't be giving anyone medals. Not under my watch." Monokuma replied, "It's called sarcasm. All of you will get used to it."

The next morning, everyone got together for breakfast. Ryuko said, "I don't think this is going to end damn well." Ryuko then took a bite of her apple. Nonon said, "Well, only one way to find out. Check out all the Mist Twst in the back." Ryuko said, "I don't drink many soft drinks. Soft drinks are not very useful in most combat." As Ryuko was saying this, Mako went into the back and got a can of Mist Twst. Mako said, "You were saying, Ryuko?". Ryuko said, "Well, is it me or do we need to go back to the gym today?" Nonon replied, "Oh yeah, let's find out if we are needed at the gym today."