Dean and Sam were in their motel room doing some research for one of their hunts.

"But Dean, I thought we got rid of it back in Wisconsin," Sam said as he looked through his laptop trying to find more evidence about the creature they were hunting. "I mean you saw it yourself. It disintegrated right in front of us."

"I know that, Sam," Dean answered Sam without looking up as he leafed through his dad's journal. "But so far, all the evidences are pointing right to it—the rotted handprint, the kids with pneumonia. What else could it be?"

Suddenly, Sam thought of something. "Hey, Dean, wait." He said as he sat up in his bed. "No. I think we were right. We did kill the Shtriga back in Wisconsin. That much we know for sure right? I mean you did say that you can kill it with consecrated iron rounds when they're feeding and that's what we did."

"Yeah."

"And these things, they take on human disguises right?"

"Yeah, Sam. We discussed all of this the first time we dealt with the shtriga. What's your point?" Dean said in frustration.

"Okay. Well, then if they can take on human disguises, then maybe…maybe they can also…" Sam seemed reluctant to continue.

"Maybe they can also what, Sam?"

"Ok, don't get too grossed out by this but what if they can…you know…"

Sam didn't even finish. He just gave Dean a look as he explained it to him, hoping that Dean would know what he was implying.

Dean didn't know where Sam was heading at first, but then he figured it out.

"No way, man."

"It's plausible, Dean."

"Are you kidding me? Don't tell me these things can actually have families of their own."

"It's not completely out there."

"That's just great." Dean couldn't believe it.

"Well…at least we already know how to kill it. We just gotta figure out where it's headed next."

"Perfect."

Dean and Sam went to the hospital dressed up in suits, once again claiming to be from the CDC. They got some information from the doctors and nurses. Afterwards, they returned to their motel room filled with frustration.

"Dangit!" Dean yelled in frustration, throwing his blazer across the room as he walked inside the room.

Sam shut the door with the same look of frustration on his face.

"That's the seventh kid, man, and they're all just getting worse. Where the heck is this freaking witch and who the heck is she? It's been days, man. You getting any connections between the kids yet?" Dean continued.

"No," Sam said rubbing his neck. "Nothing, besides the fact that they're all kids. Plus this is different than last time. Back in Wisconsin it worked its way through siblings. Now, it's just randomly picking these kids. There's no visible pattern."

Dean looked through same papers and maps that they've been using to find out the shtriga's next move while Sam sat on the bed and grabbed his laptop hoping to find some new theory from his previous research. A second later, Sam started going through his duffel bag, seeming desperate to find something.

"What are you looking for?" Dean asked, looking up from his research.

Sam didn't answer. Instead, he barged out of the room. Dean was a bit startled and confused by Sam's actions. He was about to follow Sam outside and find out what his brother was up to when Sam came back inside with something in his hand.

"Found it," Sam said, showing Dean the piece of paper.

"What?"

"Come here. Come take a look at this."

Sam set the paper out on the counter revealing a map. It was the same map that they had used back in Wisconsin when they figured out the Shtriga's pattern.

"I just thought of something. I can't believe I didn't see it before."

"What, Sam?"

"Okay, remember, back in Wisconsin, the shtriga's pattern?" Sam said pointing to the map. "It was hitting the houses circling the hospital."

"Yeah."

"Well, now, just like I said, there doesn't seem to be any kind of clear pattern this time around. I mean they're all over the city and the kids are in several different hospitals."

"Yeah. What are you getting at?"

"This," Sam said as he pulled out another map, this time a map of Ohio. "If we mark all the houses that have been hit, we just get a random pattern," he said as he made marks on the map. "See? They're all over. Some are close together, others aren't. But altogether, there are three hospitals near each one of these houses."

"Yeah, okay," Dean agreed.

"I didn't see it before because it was such a large ground to cover. But, if you take all these places together," Sam continued as he made some more marks on the map, "and add it up, look what's in the middle this time."

Dean looked at the map.

"Children's Hope Center," Dean read. "Children's Hope Center? What is that, like a daycare or something?"

"It's an orphanage."

"But wait, I don't get it. What the connection between that and the kids? None of the kids were orphans."

"No, but if you look at the files we got, then the pattern's right there."

Dean looked through each of the children's records.

"Whoa. Most of these kids were just recently adopted? So all these kids came from the orphanage?"

"Yup. And there's your pattern."

Dean chuckled. "Nice work, college boy."

"But now, our only problem is, finding out which one of the kids are next and whether or not the next kid has already been adopted or not. Besides the orphanage in the middle, the pattern's still pretty random. So who knows if this thing decides to feast at the center or not."

"Right."

The brothers paused for a moment, trying to figure out they're next move, when Dean realized something.

"Wait a minute."

"What?"

"The name. Children's Hope Center," he read again. He looked at Sam. "Does that organization sound familiar to you?"

Sam shook his head at first, not recalling the familiar name. But then it dawned on him. Both brothers realized where they had heard the name. It was the same place their two younger cousins were taken after their parents passed away. They looked at each other.

"Syd and Jason," they said simultaneously. There was fear and worry in their eyes.