Unfortunately, I think this might be true.
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"Hey." Dean said, nudging Sam's arm and making him jump. Sam hadn't noticed him, being lost in thought, one arm carelessly thrown back over the couch arm and tucked under his head. The position broadened his chest and anyone watching could see his rippling muscles under his tight shirt.
"Hi." Sam answered vaguely, his mind slipping back into the restless, dark thoughts he'd been having before. However Dean was persistent and wouldn't let him. He sat down on Sam's legs, forcing him to come to a sitting position, knees drawn up.
Dean slumped. The bags under his eyes were almost as big as Bobby's... or Sam's. "I can't stop thinking about them."
"Neither can I." Sam said. By 'them' they meant Ellen and Jo, their friends who had been alive... who would STILL be alive if only the Titanic hadn't sunk. "But it's not just them."
"What do you mean?" Dean asked, yawning widely. He stretched forward in a way not unlike a cat, showing off his own taut muscles.
"Think about it. Everyone is dieing." Sam said, and suddenly he began voicing his dark thoughts. They spilled out of him quickly, and he hardly paused for breath.
"Our father, our mother, Jessica, Gabriel... Uriel and Anna, you once and me too, our obscure cousins, Castiel twice, Joe, Ellen, Pamela, Bela, Rufus..." He was unaware of the few tears that streaked his face as he continued, "We're death magnets for everyone around us. But now there isn't anyone left. No-one except Castiel and Bobby. Think about it, every year or so someone we know well dies, and now the only two people we have left to lose is Castiel and Bobby. Soon, perhaps sooner then we think, one of them is bound to die, and this time it's doubtful whether they will come back."
There was a very long, very deathly silence.
"No." Whispered Dean. "I won't let either one die."
"Face it." Sam said darkly, "With Heaven in disarray Castiel could die at any time. And with this Eve 'mother of all' creature, it's unlikely we'll all survive." Dean got up and rounded on his brother, and Sam could see that he'd gotten to him.
"How can you say that? We'll muddle through, and we're taking them with it. I'll be damned if I'll let either one die." And he stormed away.
"I wish I could be that positive." Sam lay back again, and wondered what a world without Bobby and Cas would be like. And he hoped he was wrong and that he'd never find out.