"Well, to have your soul back, of course!" Castiel replies with a concerned look on his usually expressionless face.
You know that pukey feeling you get when you realize you have done something awful? You know when that shadowy pressure mounts inside your skull and all you want is to find the deepest darkest hole and crawl down into it and then you're afraid that there isn't one? You know when your heart feels like there's an icy hand around it and is slowly squeezing and you can't breathe?
You do? So does Sam.