Jotaro Kujo (without timestop) vs Guts.
Guts fires a volley of crossbow bolts at jotaro, he summons star platinum who easily catches all the bolts between his fingers then throws them all back with perfect precision and even greater speed, Guts swings his massive dragon slayer repeatedly while hitting all the bolts with the flat side of the blade like that time he squashed all those carnivorous insect fairies, then he leapt and brought down the dragon slayer in a two handed downwards vertical slash, star platinum stopped the blade with his bare hands then kicked guts sending him flying, guts then opened his pouch to get some of his bombs but noticed they were all gone, star platinum threw a bunch of guts' bombs at him which he stole from guts pouch without him noticing, guts shielded himself from the explosions with the flat side of his dragon slayer. Not letting up, star platinum punches the dragonslayer pushing guts back, guts retaliates with a slash but star platinum punches the blade out of its slash trajectory then with his other fist uppercuts guts in the gut making him puke blood. Guts now knowing he is outmatched in power and speed lets himself be consumed by the berserker armor, he howls in rage then he begins unleashing a supersonic storm of slahes which star platinum parries blow for blow with a fierce flurry of fists ORAORAORAORAORAORAORAORAORAORAORAORAORAORA!CLANG! CLANG! CLANG!CLANG! CLANG! CLANG! Weebs everywhere then jizzed themselves. Amidst the exchange, jotaro found a brief opening and then, "Star Finger! " Star platinum's pointing and middle finger suddenly extended at great speeds almost as if he were shooting a gun, the fingers were aimed for Guts' remaining eye and were to go through the visor, but with quick reflexes guts tilted his head to the side and instead the fingers shot and pierced through both of guts' cheeks! Guts then uses the huge serrated jaw of the armor to bite off the fingers! With his other hand star platinum then goes for a punch which Guts seemingly tries to counter with a punch of his own using his free hand but just before the fists collided the artificial hand flipped down and fired a cannonball straight at star platinum's fist point blank! A huge explosion occurs which blows both combatants back, as the smoke clears it is revealed that guts artificial hand was blown apart and unusable while star platinums fist had burns and was smoking. Jotaro then says " time to find out who the fastest gun in the west is" Guts howled and brought his dragonslayer down with one hand while star platinum goes for an uppercut, but because of the sword's longer reach it hits first and the dragonslayer cleaves straight down through star platinum's shoulder and chops his arm off! But in that very instant star platinum closes the distance and punched a hole right through Guts chest and destroying his heart! "Yare yare" jotaro mutters before passing out and dying of blood loss. K.O! Winner: JoJo