Starbase Republic focuses on the characters inhabiting the joint Federation-Romulan station and their relationships in the year 2380. The main characters inhabiting Starbase Republic are;

Captain Jason M. Craz, Commanding Officer, Human
An officer in his early forties, Jason is a veteran of the Dominion War and a tough cookie. He slowly is transitioning from being a soldier to an explorer, having led several anti-pirating expeditions and considering that the end of his combat career. Over all, he comes off as a friendly, warm fellow who takes in his crew as children or close friends, but has some definite rough patches.

Commander T'Lessa, XO/Chief Science Officer, Vulcan
The first officer of Starbase Republic is a relatively young Vulcan woman, aging in her late sixties. Her appearance of a cold, logical Vulcan perfectly meets her insides. She serves as a counter to Craz's sometimes impulsive command style, believing there to be a rational explanation and solution for everything.

Rhiana t'Valdran, Romulan Liaison Officer/Strategic Operations Officer, Romulan
The Civilian liaison between the Romulan Tal Shiar and the crew of Starbase Republic. She serves as a commander for all Romulan troops in the area, wielding her power as a member of the Imperial Royal Family, which currently holds the throne of the Empire. Her Federation Standard carries a bit of a ch'Revellion accent (somewhat resembling an Earth Russian). She has a loose friendship with some of the crew, and a romantic relationship with Captain Craz.

Lieutenant Olis Neemar, Chief of Station Security/Tactical Officer, Trill
Olis Neemar is the fourteenth host to the Neemar symbiont, a long-living worm of four centuries. Olis comes from a police background, called into Starfleet when Trill joined the Federation and has settled into the position of the head of constabulary on Starbase Republic. On duty, she works casually with a friendly sense to anyone she meets, even suspects. Off the job, she lives decadently, drinking and following her impulses of romantic conquest. She is an incredibly flamboyant individual, enjoying life to the fullest.

Lieutenant Leya Shaw, Chief of Station Operations, Bajoran
Leya Shaw is the head of engineering on the station, and considered to be one of the most ingenuitive in Starfleet. She is a Bajoran of more secular beliefs, not worshiping the Prophets but still respecting them. She does not wear an earring, having destroyed hers some time ago in an argument. A small rift stands between Leya and Captain Craz, stemming from that same argument. She is currently married to Patrick Shaw.

Counselor Laurina Morganth, Station Counselor, Betazoid
The reserved persona of Laurina Morganth, station counselor, is one that many of the crew find to be a comforting ear and a friend who many come to with problems. She uses her telepathy with high morals, never intentionally looking into others' thoughts without their direct permission. Her professional air and cool with is one that playfully clashes with Olis Neemar's, the counselor being the teasing center of affections of the Trill.

Major Patrick Shaw, Head of Marines, human
Patrick Shaw is a member of Starbase Republic's crew as a matter of chance. He was born in 2004, and a temporal dislocate. Originally, he was a pilot in the United States Marine Corps, and due to an accidental intervention by Republic's crew, brought Shaw back with them to the twenty-fourth century. He currently serves as the head of SBR's Marines.

Lieutenant Jodi Wilson, Chief Pilot, Cerva (human in disguise)
Jodi is the head of the SBR piloting staff, assigned from the T'Kemeril before. She comes off as a quiet, serious person, but in reality has a secret. She is a sleeper agent, planted in SBR's crew by the Cerva, a race of pirates. She has already committed sabotage, and used her position on the station to cover it up. She secretly despises having to live on Republic, with only one solace among the crew, Shoy Craz.

Cadet Shoy Craz, Science/Engineering Cadet, Human/Andorian
At first glances, Shoy Craz is a short, unimposing Andorian who appears to spend five minutes less than he should getting prepared in the morning. He is quiet, unsocial, and usually nervous and awkward in social situations. He approaches life with a naive curiosity, often times giving him one of the more positive outlooks on the station's crew. He is currently filling his junior and senior years in the field, serving under T'Lessa and Leya in his studies. Nephew to the Captain, he finds himself at the center of Craz's fatherly attentions, often trying to help Shoy understand the darker realities of life. Against regulations, he is having a secret romantic affair with Jodi Wilson, a commissioned officer.

Kimberly Patterson, journalist(Federation News Service), Human(or as close a reporter can be)
Patterson is a journalist attached to SBR, currently with a vendetta to find something wrong with Captain Craz, of whom she is sure is corrupt. She is known to pop up with her holocam crew at the most inconvenient of times, often provoking Jason to remark his continued regret of quitting alcohol.