The year is 1954. There are scientists examining an island in the Pacific Ocean. With them is a nuclear weapon, perched on a tower. A timer goes off, and the scientists flee the scene. Once they're all gone, the weapon goes off, unearthing a massive creature, which glares with hate in it's eyes. Years later, in 2018, at a place known as ScumLabs, there are three siblings, a 16 year old boy named George, a 16 1/2 year old girl named Lizzie, and a 16 1/2 year old boy named Ralph. A scientist comes in, saying that the lab is ready for them. In a large room, there are four vats, one with a picture of a gorilla on it, one with a picture of an alligator on it, one with a picture of a wolf on it, and one with a warning label on it. A bearded scientist arrives on the scene, revealing that George, Lizzie, and Ralph are going to be part of an experiment involving animal DNA and chemicals. Another scientist then enters the room with 6 hypodermic needles, each with a sample of something from the four vats, which contain gorilla DNA, alligator DNA, wolf DNA, and a mixture of various chemicals, respectively. This scientist then injects each into one of the siblings, the gorilla DNA into George, the alligator DNA into Lizzie, the wolf DNA into Ralph, and the chemical mixture into all three siblings, then something happens. They begin growing, their muscles become bigger, George starts growing hair on his body, Lizzie develops scales and sharp teeth, and Ralph grows hair and a dog-like snout. Before anybody can say anything, the three siblings are now 20-foot tall beasts. George is a giant gorilla, Lizzie is a giant dinosaur-like creature, and Ralph is a giant bipedal wolf.
The scene changes to San Francisco. People are living their normal lives when a child at the beach spots something in the water. It's a row of maple leaf-like spines, literally cutting their way through the water, heading straight toward the city. Meanwhile, in another part of the city, the mutated George, Lizzie, and Ralph, come crashing their way into the city, and begin destroying everything in their path. Meanwhile, at the beach, a large mass comes out of the water, and once the water falls back into the sea, a 400-foot tall, dragon-like beast with a row of spines on it's back, can be seen. This creature comes ashore and begins it's own spree of destruction. Eventually, this creature and the monsterized siblings meet in the center of the city, where they engage in combat, with neither side able to best the other. Eventually, however, the larger beast emerges triumphant, and devours the siblings. The creature then continues it's spree of destruction, unopposed.
