Author Note: Hello I thought about doing a Left 4 Dead crossover with Lizzie McGuire since nobody has done it yet. :D

Chapter One: The Green Flu

Lizzie, Miranda and Gordo watch the news at 8pm. The east coast has been quarantined and the central and west coast has been on watch for the green flu symptoms. "1,098 people have been quarantined in their homes, yet over 3,750 have died from this flu. For safety procaution, always wash your hands, wear a mask from getting this flu and stay away from others who have fever/flu-like symptoms-" Lizzie turned off the TV, she is scared out of her mind of what is going on. "I hope this flu will pass..." She says, her voice trembling. "Don't worry, Lizzie. Remember the whole Swine Flu scare and only a few people died from it, yet it passed." Gordo said in a low voice, it is the summer of 2008, near autumn and they are between 18 and 19.

Ten minutes earlier in Las Vegas.

A woman snuck past the quarantine border, full of cuts and bruises of her wars against all the infected and special infected. She is carrying her baby who is ill, she kept the baby covered in blankets yet sleeping. "Don't worry, we are almost to safety. I think we are immuned to this flu." She walks towards the city, she starts crossing the road as a car stops in front of her. "Lady, are you alright?" The man called out. "Help, my baby... My baby is sick... Please take us to the nearest hospital." The man saw the condition she was in. He turned off the radio right before the broadcast came on about a woman who snuck past the Quarantined border. "Get in, there is a hospital 6 miles from here." She quickly got in and looked at her baby, the skin was so pale that you can tell it is close to dying. "Don't worry... We will get you help..." Then she coughed a few times and out came a bit of blood. Her eyes open wide as she wipes the blood on the blanket. Oh shit... Oh shit... No!

The McGuires locked their doors and windows after hearing the recent broadcast about the woman sneaking past the border, though letting Lizzie have Miranda and Gordo stay the night since it wasn't safe for them to leave the house at night with what is going on.

"Do you think they will catch her? I heard she has a baby with her..." Miranda's voice was distant. "Don't worry about it, they have the police and military looking for her. They will find her." Gordo said reassuring her. They stayed in Lizzie's room since upstairs seems more safe than being downstairs where somebody can just look through the window, see them and attack them. Everybody went to sleep at 1:52am after watching a few comedy movies to keep their mind off of things.

Sam McGuire walked down the stairs to get a glass of water when he heard frantic knocking at the door, it scared him as he was not expecting it. "Please, somebody let me in..." Sam quickly went to the door and opened it, there was a girl at the age of 11 standing there, she had blood on her white pajamas shirt. "My dad attacked mom, there is blood everywhere." She cried, scared witless. Sam was in shock, he was friends with the girl's dad George Hamilton. He went to college with Sam and George came from an mormon family where he would never hurt a fly. 'What the hell is going on...?' Sam questioned himself quietly. The girl was the youngest daughter of 4 girls, her name was Amanda Hamilton. "Amanda come-" He started as Amanda lunged at him, taking a bite out of arm. His reflex kicked in as he smacked her hard across the face, she hit the floor leaving a loud thud. He heard a whimper, from her and then a growl. "What are you doing?! I am trying to help you!" He cried out not long before she got to her feet, snarled at him, around her mouth was blood. 'Oh shit...' He pushed her hard enough for her out the front door and locked it. A scream was heard and rapid pounding on the door was heard, Jo McGuire came down the stairs. "S-Sam? What is going on-?" "Amanda Hamilton attacked me..." He rushed towards the bathroom to attend the wound as it blood profusely. "George's little girl? Sam, what is going on?!" She demanded, worried. "Jo, please. Wake the others up, we can't be in seperate rooms with what just happened." He ushered, bandaging up his wound. Jo went upstairs to Matt's room, woke him up. "Matthew, wake up... Wake up now." Matt groaned and turned towards his mom. "What is it?" He asked rubbing his eyes. Matt has just turned 16 this month of July. "Come down stairs, something has happened." Matt quietly, but alarmly obeyed, he has grown from his prankster self of when he turned 14, the teachers told the McGuires that Matt has an high IQ, just never set his mind to things until then. Jo then walked down the stairs with Matt, Gordo, Miranda and Lizzie. "Where's dad?" Lizzie asked, rubbing the sleep out from her eyes, yawning. "He is in the living room..." She said taking a deep breath. "Sam, I got the kids..." Sam walked from the living room, the bandage on his arm has blood already soaked through. "D-Dad? What happened to your arm?" Asked Matt, he now wondered if the flu has hit California. "I was attacked by Amanda Hamilton, she said that her mom was attacked by her father." He said calmly, wincing from the throbbing pain in his arm. Jo leaned over and kissed Sam and the lips, "Don't worry, if we keep our blinds closed and doors locked, we should be fine... Right?" Jo asked, hoping she was right. "Yeah... Yeah." He said. They all closed every blinds in the house and stayed in the livingroom. It is 3:37am now, Gordo, Lizzie and Miranda went back into Lizzie's room, looking out the window while they heard screaming down the street. Lizzie tried to hold back tears while Miranda and Gordo just hugged, they all fell back to sleep while Jo kept complaining to Sam about feeling cold all of a sudden...

They woke up to Matt in her room, his eyes are puffy from crying. "Wake up... Wake up... Dad is dead, mom has gone crazy." Lizzie woke up, "W-What?" she looks next to her, only Gordo was by her side. "Where's Miranda?" She panicked. Gordo sat up, "She told me an hour ago that she had to use the bath...room..." He then realized that it usually takes 2-3 minutes to use the toilet, looking at his cellphone it is only 9:18am. They heard soft crying from downstairs. "We need to help your mom." Gordo said, now standing up. "No... No, you can't. I was downstairs with them when it happened. Mom kept complaining about being cold, she got sick and then attacked down, there is blood everywhere and I doubt he is alive." He said blocking the door, "We need something to defend ourselves." Gordo said looking around. "What about Miranda?" Lizzie says sniffling, shaking in fear. "She must be hiding in the bathroom, I told her to hide when I bumped into her."

They quietly walked outside of the bedroom and towards the bathroom door. "Miranda, are you in there?" Matt whispered, the sobbing got closer as they saw Jo, or what was Jo. Her hair was in her face while she was covered in blood, her clothes has been shredded to where her breasts has been exposed though there was a long gash on the right breast from trying to rip her clothes off. Lizzie noticed that her mom's fingers has become very long claws. Miranda opened the door, "Is it safe to come out?" Jo snapped her head towards them and started growling, her skin is light gray as her eyes shined like animal's eyes do when the light reflects back to the retina. The kids quickly went to the parent's room and looked for weapons, they heard Jo resume to crying. "S-She didn't attack us..." Matt said slowly, confused of why she didn't attack them when she immediately attacked and killed their father. Lizzie found a pistol, Miranda found a magnum, Gordo a rifle and Matt had his dad's autograph signed wooden baseball bat. Sam taught their kids to shoot guns 2 years ago for safety, took them out south 2 hours away from home into the desert to shoot some targets.

Matt and Gordo went and grabbed some clothes (Mostly only Matt's clothes) the girls grabbed what was in the dresser and closet along with personal items, yet they took a hand-held radio with them to listen to the broadcast. The sobbing seemed closer, Lizzie thought she heard her name in the crying but kept her guard up. "M..Mom?" Lizzie whispered...

Author's note: Well then! I am tired and my poor brain can't process anymore for right now. x.x

Will be back for more! :D