A/N: I hope you like this. It's just another Isabel vs. Amy and Dan. Please review, follow, favorite, bla, bla, bla...what else am I forgetting? Oh yes, don't think for a second that I own the 39 Clues!

Enjoy! :)

They were doomed.

Amy and Dan stood isolated in the hotel corridor. So did Isabel Kabra, but only for a moment. Then the surprise subsided into a sickly sweet smile.

"Ah, Amy and Dan." she purred, "This is quite an opportunity. Well for me, anyway. For you I don't think it's going to be so good."

Amy spat, "And why's that?"

"Because," Isabel said, "I know more than you know. And if you don't do as I say, you'll be very sorry."

"I'm sorry." Dan said sweetly, "But we're on a task. For your boss I believe. So the deal's off."

Isabel stared darkly and at the boy. "What boss?"

"Vesper One. You know, the guy who's wanting us to get all these strange and valuable items? Yeah, him. I bet he wants you to do something too."

"You don't know a thing about that." Isabel growled.

Amy pried, "So you work for Vesper One do you?"

Isabel's irritated expression intensified but she didn't respond and instead produced a gun from her purse. She turned Dan.

"The serum. You have it, don't you?"

Amy gasped. Does Dan really have...?

Dan looked at the ground. "No..."

Isabel aimed the gun at his head.

"Don't lie to me, idiot boy. Where is it?" She pressed.

"I haven't made it all yet." Dan mumbled.

She cursed and slammed Dan against the wall. "Why haven't you made it yet?"

Amy shrieked, "Let go of my brother!"

Isabel grasped the squirming boy by the neck. She swiveled the gun at Amy.

"And you darling have a task to do from this supposed Vesper One, so why don't you go along and do what he says."

"Without Dan? Not on my life!"Amy said.

Isabel smiled maliciously. "We'll I'm afraid he's tak-"

Before she could finish her sentence, Dan kicked hard at Isabel's knee and the woman buckled. Amy saw this and rushed forward toward her. She collided into her just as Dan recoiled from Isabel's grip.

"Aargh!"

Then Isabel's elbow smashed against the fire alarm glass and enabled the siren as she fell. Hotel Room doors opened and the guests rushed out in blind panic as they raced around the fallen body. An older man recognized Isabel and crouched to the floor to help her up.

"I know you!" He exclaimed, "You're that lady who runs that organization-what is it- AidsWorksWonders? I think what you do is great! Good lord, is that a gun!?"

She regarded him as an unwanted pest but now she took advantage if him.

"These wild teenagers were trying to kill me! But I grabbed the gun off them!" Isabel declared.

The man turned to Amy and Dan. "You're coming with me!" he announced.

They both turned and sprinted off in a panic. They had to get away fast.

"HEY! Come back! There's a fire in the building!" The man shouted.

Amy glanced over her shoulder to see the man marching towards them, and a seething Isabel following closely behind.

"We have to get to the stairs!" Dan said.

At that moment, they crashed into Jake and Atticus.

"There you are, we were hunting all over for you guys!" Atticus said with relief.

Dan replied, "Yeah well we have a couple more hunting for us."

"The Wyomings?"

"Nope, even worse."

Just then, Isabel and the man rounded the corner towards them.

Isabel shouted, "Get those criminals!"

They all turned and ran toward the staircase.

The foursome pushed open the stairwell door and leaped down the steps four at a time. They could hear the pounding footsteps of their pursuers, both Isabel and the man making shouts of protests. Then the worst happened. Amy tripped on Jake's foot and fell onto a platform on the staircase.

"NO!" Dan screamed.

Jake and Atticus halted. Dan tried to lift Amy up but it was failing.

"I've twisted my ankle!" Amy sobbed.

The sound of Isabel and her companion was getting ever nearer. Dan calculated that it would only take half a minute for the two to reach them.

"We can't leave her here, we'll need to carry her!" Dan said rapidly.

Jake scooped her over his shoulders and with a nod they all resumed their escape, Jake being more careful especially. In about a minute, they had reached the bottom and were about to open the door.

Dan panicked. "I can't open it!"

"Let me try!" Jake offered as he tugged on the door handle whilst having a moaning Amy on her shoulder. They could sense Isabel and the man rushing down the stairs. They were close. Then they appeared on the last flight of stairs, yelling for them to stop.

"Hurry!" Atticus urged.

Jake said through clenched teeth. "I'm...trying..."

Then the door burst open and in an instant, Dan, Atticus and Jake holding Amy floored it out into the masses of people surging out of the hotel main entrance. They entwined themselves into the crowd to prevent being spotted. Dan glanced behind him and saw them both - the man frowning as he tried to search through the hoards of people and an even more infuriated Isabel. He knew that if she spotted them, she would kill them.

They all managed to exit the hotel and they were now running together, away from the building. After a few blocks, they came to a stop outside an old factory.

"We need to get her to a Doctor." Jake said resolutely, putting Amy down. "We can't go on with Amy having a broken ankle."

"It's only twisted." Amy said, trying to sound meek but instead it came out tense.

"There's a public hospital not that far away." Atticus complied. "It's just down the road."

Dan said, "Great, let's go there!"

"Going somewhere?"

All four turned to see Isabel standing victoriously in front of them.