Shippo and Satsuke (the girl from the stone flower and shippos 1st love) are all grown up and married.
Rin and Kohaku are also grown but not married.
Kagome and Inuyasha are married and have a child his name is Inutaesho (same as Inuyasha's Dad).
Sango is married to Miroku and have 1 boy named ? ( i dont have any names so comment me a nd give me some) and also 4 daughters ( no names)
Sesshomaru is married to...Kagura! (for those of you that didn't know Kagura falls in love with Sesshomaru in the series).
The story takes place in modern time Japan.