Based on Season 2, Episode 12 "Nightshifter"
Prompt: "I know about Sam too; Bonnie to your Clyde" – Henricksen
"Yeah, well that part's true" – Dean
The most worrying part about agreeing to that statement, Dean realised later, was that Clyde had been a raging homosexual, and to be honest, that was a confession Dean wasn't quite comfortable with.
Although on the same subject, labelling Sam as the girl was pretty accurate. He was the standard bottom in their relationship (apart from that one night in Arizona which they never talked about because Dean hadn't been able to walk for a week.)
But the more Dean thought about it, the more unhappy he was that some FBI Agent was trying to out him before he was ready.
"You're reading too much into it Dean," Said Sam, interrupting Dean's thoughts, "He just meant we're mad psycho-killers on the run."
"Yeah, 'cause that doesn't sound nearly as bad," Dean quipped back. He glanced across at Sam all got up in the SWAT gear.
"You know, we're gonna have to lay low for a few days. Probably stay cooped up somewhere..."
"I'm sure we can find plenty of ways to keep ourselves busy," Sam responded, smirking.
With that, Dean floored the gas.