Witch Hazel (voiced by Tress MacNeille, replacing the late June Foray respectively)
Ever since Tress MacNeille voices many different elderly women characters, she's most perfect to take over from the late June Foray to provide Witch Hazel's voice in the reboot.
Granny, the nurse of ACME Looniversity (voiced by Candi Milo, replacing the late June Foray respectively)
Candi Milo voices many elderly women characters including Madame Foster on Foster's Home for Imaginary Friends, she's most perfect to take over from the late June Foray to provide Granny's voice in the reboot.
Wade Pig and Sappy Stanley (both voiced by Jim Cummings, replacing both the late Jonathan Winters and the late Joe Alaskey respectively)
Jim Cummings voices many different types of cartoon animated characters including Pete in the Mickey Mouse cartoon series and Pooh and Tigger in the Winnie the Pooh cartoon series, he's most perfect to take over from both the late Jonathan Winters and the late Joe Alaskey to provide Wade Pig and Sappy Stanley's voices in the reboot.
Plucky Duck (voiced by Jason Marsden, sounding like a mix between Daffy Duck from the Looney Tunes franchise and Danger Duck on Loonatics Unleashed, replacing the late Joe Alaskey respectively)
Jason Marsden voices Danger Duck on Loonatics Unleashed, he's most perfect to take over from the late Joe Alaskey to provide Plucky's voice in the reboot.
