Anna was the first woman to be injected with the remake of the super-soldier serum, she was also the last. It worked like it should have. She was the first S.H.I.E.L.D. agent. People knew Captain America as a hero, but Anna got to know more of the hero. Steve. Steve was her best friend. She had always loved Steve just more than she hoped. When going to training to be an agent she met a remarkable women, Peggy Carter. Anna and Peggy became great the war ended she was injected with the serum. The government cut off the research so she was the last to get the serum. Anna didn't stop there. She founded S.H.I.E.L.D serum has kept her young and healthy. While staying young and healthy for more than 70 years, you become lonley. She worked in the field for 70 plus years makes enemies as the decades went by. When he woke up Anna was right there next to him. She was his only comfort in the traumatic change. The world is changing right before both of their eyes and its a change they had just have to get used to.