Marie is spinning and twirling and stabbing in the middle of the darkened, decrypt church. Her knife-a family heirloom that she was told never to ask about-seems to be the only thing that works against these monsters. So Marie is the only one who can stop them.
There's a gunshot to her right, so she turns and see two men, one much taller than the other. She, like all hunters now, knows the Winchesters on sight. She doesn't need them. She turns to tell them so, with a smirk on her perfectly made-up face. A monster rips off her head.