Top Ten Reasons Sherlock Holmes Never Married:
#10. Getting nagged at every time he goes out on a case.
#9. Coming home to find his entire lab in the trash.
#8. "Stop playing that violin and come to bed!"
#7. The Irregulars not being allowed in the house.
#6. Catching hell for disappearing for those three years.
#5. "Are you and Dr. Watson going to yak all night?"
#4. Mrs. Hudson getting fired.
#3. "Take that nasty pipe and smoke it outside!"
#2. Suspicion about the photo of Irene Adler.
And the #1 reason:
"I invited that nice Professor Moriarty for dinner this evening."