I do not own OTH just an avid watcher.
Brooke has suffered through the worst type of thing and she needs her best friend Peyton there to make the pain go away but Peyton is in LA when a friend ends up on her door step Peyton takes a step back and re-evaluates her life.
Peyton and Lucas never betrayed Brooke.
Lucas and Lindsey get married and Lindsey gets pregnant and they live a semi-happily life.
Brooke needs Peyton's help to figure out what it is she wants and evaluate what's important in her life.
Mouth and Millicent is still together.