Cyberdome was a framework. A thing that works like microwave, type the food and cyberdome creates it using crispr.
Rufus, btw, could create the mindframe (GL network inside Cyberdome) to solve part of mind deceases like depression.
The Union could using Cyberdome to creating organ.
Pretty much applications for Cyberdome creating life and environment inside.
But, to create an "organ" you will need sort of nano machines. When war begins Cyberdome got militaryzed and Nano's out there.
Rufus stop working mindframe from mind deceases to more military thing.
The Union begins to enlist intellectuals to advance technology and a war would be necessary to a new leap of mankind technology. Solving the food and deceases problems.
The Polity treat things like that a authoritarianism way to do things.
When Union captures Julian Chase, they dissecates him (making the backup Julian the only one). Mergin them to Nano tech because Cyberdome could create life, nanos, organ's and replicates humam mind.
The Nanos and Nemesis could be the most threat from Union by now.
But, there is Caliban. An Artificial Mindframe without an Cyberdome. That could receive everyone without genlock compatibles. There no need to use cyberdome tech.
The Caliban's mind could be used to create a new great army. And the Mindframe from Cyberdome could meta-mind gen-lock compatibles to create a new form a super human being. More psych resilient. There is no reason to treat depression and mind deceases. You could transfer part's of it across humans.
The Genlock team become a new type a human being.
The Caliban mind could lead the war to a new level.
The Nano's already bring the war to a new level but could expand using mindframe tech to another monstruos things.
Mindframe SDK (Caliban) could be used on Strider tech and everyone on Vanguard could fight this war.
And GL Team could be free now to work every part of the globe.