Angela and Brennan had been at a club the night before, the first time Angela had managed to drag her out since the "meth club incident." Brennan had about three drinks; Ange had a "few" more, knowing Bren could drive her home. Brennan warned her that for her size that many drinks would give her a massive hangover. Angela had just said live in the moment and pulled her to the dance floor. So Brennan wasn't surprised Ange was late to work the following morning.

"Where's Angela?" Cam asked the team assembled on the platform (minus Booth), "She probably is trying to ward off her major hangover headache," Brennan offered. "We went out to a club last night and she was drinking, a lot…" Brennan voice trailed off. "We have a body people," Cam said. "Brennan go meet Booth. The rest of you get ready and let me know when Angela gets here".

They were working of the skeleton for a while before Brennan said "I have the skull for Ange." "She's still not here Dr. B" Hodgins said looking up from his microscope. Brennan frowned and went to call her, slightly worried. No answer, she got an answering machine. Two hours later there was still no word from Ange and everyone was becoming concerned. They called her repeatedly with no answer at home or on her cell. Booth and Brennan went to her apartment and knocked on the door. No answer, no surprise. Bren kicked the door down. "I'll pay for I new one," she told a surprised Booth.

There was no sign of her anywhere in the apartment. They could tell she had been in bed because the sheets were a tangled mess. They called the lab to make sure she hadn't appeared there and searched for signs of foul play. Booth found a shattered vase, which Brennan identified as one Ange had made herself. Booth called the forensic team at the FBI "signs of a struggle" he told them. He shrugged at Bren "A white lie Bones, we found partial evidence and she's family". Brennan agreed hoping to see Ange again soon.

The lab tech stormed the place searching for blood or other evidence. Booth and Brennan went to update the lab and wait for Angela's return. By this time they were all getting nervous. "Who would hurt her?" Booth asked, "She wasn't a big time author, or a millionaire, she was just an artist" "She is just an artist" Hodgins corrected "and she's not 'just' anything. But I agree she's had no threats, she is kind to everyone". They continued to distractedly work on the skeleton until Zack almost dropped a bone. Cam ordered them all to the couches until Ange arrived. They sat there silently waiting anxiously for news. "Tell me something Bones" Booth said coming back from his journey to the FBI offices. "There are 752 ceiling tiles on this section of the ceiling and Cam ordered us to stop working until Angela is back".

At this Booth goes to talk to Cam "We have a murderer to catch Camille" he hissed. "Zack almost dropped a femur, Seeley. They are missing one of their closest friends give them a break" she whispered rubbing her forehead, exhausted and upset. "She's my friend too Cam." he said, "I'm worried too. I need to keep busy." "Go sit with Brennan" she said. He tugged her over with him "There's something you need to know." He then shared with the entire team that it looked like a definite struggle and that she was declared officially missing.