I was on my computer searching for cases while Dean went to get beer and Sam slept on the bed. I heard a thump and I turned around to see Sam on the floor breathing heavily.

"Sam are you okay?" I asked helping him up.

"Yeah." Sam said before Dean walked in the door.

"Sam?" Dean asked.

"I had another vision. We need to go to a town called Rivergrove. In Oregon." Sam said putting on a shirt then his jacket.

"Alright, let's go." Dean said before I shut my laptop and grabbed my bag.

When we got into the car Sam got on his GPS app on his phone and looked up Rivergrove.

"There are only two towns in the U.S called River grove." He said.

"How come you're so sure its the one in Oregon?" Dean asked.

"There was a picture. Crater Lake." Sam replied.

"Okay, what else?" Dean asked.

"I saw a dark room, some people, and a guy tied to a chair. And you killed him. You thought there was something inside him." Sam said.

"A demon? Was he possessed?" I asked.

"I don't know." Sam answered.

"All your weirdo visions are always tied to the yellow-eyed demon somehow. So was there black smoke? Did we try to exorcise him?" Dean said.

"No, nothing. You just plugged him." Sam replied. "That's it."

"Well I'm sure I had a good reason." Dean said.

"I sure hope so." Sam said.

"What does that mean?" Dean asked. "I'm not gonna waste an innocent man."

Sam was silent.

"I wouldn't." Dean exclaimed.

"I never said you would." Sam responded.

"Fine."

"Fine."

"Look, we don't know what it is. But whatever it is that guy in the chair has something to do with it." Sam said. "So lets find him and see what's what."

'Fine."

"Fine."

We drove the rest of the way to Rivergrove in silence. When we got there, Dean parked the Impala and Sam pointed at a man.

"He was there." Sam said.

Them man was outside on his porch putting a fishing rod together. We got out and started walking to him.

"Morning." Dean said.

"Morning, can I help you?" The man replied.

"Yeah. Billy Gibbons, Frank Beard, Alyssa Jones. U.S Marshalls." Dean said as we took out our badges.

"What's this about?" He asked.

"We're looking for someone." I said.

"A young man, early 20s. He'd have a thin scar right below his hairline." Sam said.

"What did he do?" The man asked.

"Nothing. We're actually looking for someone else, but we think this young man could help us." Sam replied.

"Yeah, he's not in any kind of trouble or anything. Yet." Dean said. "I think you know who he is, Master Sergeant. My dad was in the corps. He was a corporal."

"What company?" He asked.

"Echo 2-1." Dean answered.

"So can you help us?" Sam asked.

"Duane Tanner has a scar like that. But I know him. Good kid, keeps his nose clean." He answered.

"I'm sure he does. Do you know where he lives?" Dean asked.

"With his family, up Aspen way." He said.

"Thank you." I said before we left.

We were walking on the sidewalk and I ran into a wooden post.

"Hey." I said to Sam and Dean.

I pointed at the word.

"Croatoan?" Dean asked.

"Yeah." I said.

Dean looked confused.

"Roanoke. Lost colony. Ring a bell?" Sam asked Dean. "Dean, did you pay any attention to history class?"

"Yeah. The shot heard around the world, how bills became laws." Dean replied.

"That's not school, Dean. That's 'Schoolhouse Rock.' Sam said.

"Whatever." Dean replied.

"Roanoke was the English's first attempt to colonize America in the late 1500s. This man left Roanoke to get supplies that they really needed from England. When he tried to come back he was stopped by the battle with the Spanish Armada. Two years later he finally came back and there was no sight of the colony. The only clues they had to where the colony went was the word 'Croatoan' on a tree and the letters CRO on a door." I said.

"There were theories, Indian raid, disease, but nobody knew what happened to them. They were just gone." Sam said.

"You don't think that's what's going on here." Dean responded.

"Whatever I saw in my head sure wasn't good." Sam replied.

"What do you think could do that?" I asked.

"Well, Sam's visions always has something to do with the yellow-eyed demon." Dean answered.

"We should get help. Bobby, Ellen maybe." Sam said.

"Good idea." Dean said taking out his cellphone.

"I don't have a signal." Dean said.

Sam and I checked out phones.

"I don't either." Sam said.

"Neither do I." I responded.

We walked over to a payphone and Dean tried to use it.

"Line's dead." He said. "I'll tell you one thing. If I was gonna massacre a town that'd be my first step."

We decided to drive to Duane's house to see if we could find him. We knocked on the door and a guy younger then us opened the door.

"Yeah?" He asked.

"Hi, looking for Duane Tanner, he lives here, right?" Dean said holding his badge.

"He's my brother." The guy answered.

"Can we talk to him?" I asked.

"He's not here right now." He said.

"Do you know where he is?" Dean asked.

"He went on a fishing trip up by Roslyn Lake." He said.

"Your parents home?" Sam asked.

"Yeah, they're inside."

"Jake who is it?" A man called coming to the door.

"Hi. U.S. Marshalls sir." Dean said. "We're looking for your son Duane."

"He's not in trouble is he?" The man asked.

"No, no, no. We just need to ask him a few routine questions." Dean replied.

"When is he due back from his trip?" Sam asked.

"I'm not sure." He answered.

"Maybe your wife knows?" I asked.

"I don't know, she's not here right now." He said.

"Your son said she was." Dean said.

"Did I?" Jake asked

"She's getting groceries." The father said, "So when Duane gets back, is there a number to get ahold of you?"

"No, we'll just check in with you later." Dean said

"That was kind of creepy right?" Dean asked when we walked down the steps. "A little too stepford."

"Big-time." Sam answered.

We went around the house and looked through a window. Mrs. Tanner was tied up to a chair. The dad cut Jake's arm with a knife. We loaded out guns and we broke through the back door.

"Put the knife down!" Dean yelled before ran at him with the knife.

Dean shot him in the chest twice and once in the stomach. Before we were able to get Jake he jumped out the window Sam tried to shoot him, but he ran into the woods.

We untied and brought her to the clinic. Sam and I brought her into the building and Dean grabbed Mr. Tanner.

"Hello?" I called when we went through the door.

"We need a doctor here." Sam said

"Mrs. Tanner what happened?" A young woman came out.

"She's been attacked." I said.

"Dr. Lee." She called out.

The doctor came out and looked at Mrs. Tanner.

"Bring her in." Dr. Lee said.

We listened to the story Mrs. Tanner told the doctor then Dean told us that we had to talk.

"Those guys were whacked out of their gourds." Dean said when we went into the other room.

"What do you think, mass possession?" Sam asked.

"If it is a possession there could be more." Dean replied. "Who knows how many, it could be a shriner convention."

"Of course that's how you wipe out a town. You take it from the inside." I said.

"I don't know. We didn't see any demon smoke with Tanner or any of the other usual signs." Sam said.

"Well something turned him into a monster." I said.

"You know Sam, if you would've taken out the other one there would be one less to worry about." Dean said.

"I'm sorry. I hesitated, Dean, it was a kid." Sam replied.

"No it was an 'it'," Dean responded. "It's not the best time for a bleeding heart, Sam."

Then Dr. Lee walked in.

"How's the patient?" Sam asked.

"Terrible. What the hell happened out there?" She replied.

"We don't know." Dean answered.

"Yeah. Well you killed my next-door neighbor." She said,

"We didn't have a choice." Dean said.

"Maybe. But we need the county sheriff." Doctor Lee said.

"The phones are down." I said.

"I know. Please tell me you have a police radio." She replied.

"We do, but it crapped out like everything else." Sam said.

"I don't understand what's happening." Doctor Lee said.

"How far is it to the next town?" Dean asked.

"About 40 miles to Sidewinder." She answered.

"I'm going to go down there, see if I can get any help." Dean said. "My partners will stick around and keep you guys safe."

"Safe from what?" Dr. Lee asked.

"We'll get back to you on that." Dean said before leaving.

Sam and I sat with Dr. Lee in a room that had Mr. Tanner on a table.

"Huh." Dr. Lee said.

"What?" I asked.

"His lymphocyte percentage is pretty high. His body was fighting off a viral infection." She replied.

"Really? What kind of virus?" Sam asked.

"I can't say for sure." She said.

"Do you think an infection caused him to act like that?" I asked.

"Not that I ever heard of. Some can cause dementia, but not that kind of violence." Lee said. "Besides, I've never heard of one that can do this to the blood."

"Do what?" Sam asked.

"There's this weird residue. If I didn't know better I would say it was sulfur." She said.

Sam and I looked at each other before turning back to the doctor.

"Sulfur." Sam repeated.

We told Mrs. Tanner about it, "Are you saying my husband and Jake had a disease?"

"That's what we're trying to find out." Dr. Lee replied. "Now, during the attack, did you have any direct contact with their blood?"

"Oh my god. You don't think I have this virus, do you?" Mrs. Tanner asked.

"Beverly, I don't know what to think." She responded. "But with your permission, I would like to take a blood sample."

Mrs. Tanner sighed before grabbing onto Dr. Lee. She hit her in the jaw. Then she pushed Sam into the cabinet then came after me with a scaple.

I concentrated and a metal box flew off the counter and hit her in the head and she fell to the ground unconscious. Dr. Lee took a sample of Mrs. Tanner's blood and we put her in the storage room.

"What if we all have it?" Pam asked. "What if we all go crazy?"

"You got to stay calm. All we can do is wait." Dr. Lee replied. "The Marshal is bringing help."

"I can't. I have to go."

"Pam?" The doctor questioned.

"No, you don't understand. My boyfriend is out there. I've got to make sure he's okay." Pam said before leaving the room and Sam went after her.

Then I heard Dean's car out front.

"Finally." I said standing up.

I walked to the door and unlocked it.

"Did you guys get to a phone?" Sam said walking up behind me.

"Roadblock." Dean replied, "I'm going to have a word. Doc's inside."

"Alright." The man from earlier said before walking away.

"What's going on out there, Dean?" Sam asked.

"I feel like Chuck Heston in the Omega Man." Dean responded, "Sarge is the only sane person I could find. What are we dealing with, do you know?"

"Doc thinks it's a virus." I replied,

"Okay, great. What do you think?" Dean asked.

"I think she's right. She found sulfur in Mr. Tanner's blood. I think the infected are trying to infect others with blood-to-blood contact." I said.

"So a demonic virus?" Dean questioned.

"More like a demonic germ warfare." Sam replied, "At least it explains why I've been having visions."

"It's like a biblical plaque." Dean commented.

"You don't know how right you are." Sam said. "I've been pouring through dad's journal. I found something on the Roanoke colony."

"And?"

"Dad had a theory about 'Croatoan.' He thought it was a demon name. Sometimes known as Daeva or Reshef, a demon of plaque and pestilence." Sam said.

"That's terrific. But why here? Why now?" Dean replied.

"I have no idea. But Dean, who knows how far this thing could spread. We've got to get out of here. We have to warn people." Sam said.

"They got one. In here." The Sargent exclaimed.

"What do you mean?" Dean asked as we walked to the room.

"The wife, she's infected." I said.

"We've got to take care of this." Mark said. "We can't just leave her in there. My neighbors. They were strong. The longer we wait the stronger she gets."

Dean cocked his gun and we walked to where Pam and Dr. Lee was.

"You're gonna kill Beverly Tanner?" Pam asked.

"Doctor, could there be any treatment?" Sam asked. "Any cure for this?"

"Can you cure it?" Dean asked.

"For god sake. I don't even know what 'it' is!" Dr. Lee exclaimed.

"I tole you its a matter of time before she breaks through." Mark said.

"Just leave her there. You can't just shoot her like an animal." Pam said.

"Sam." Dean called before going to the door.

Sam opened the door and Mark and Dean went in there with their guns pointed at Mrs. Tanner.

"Mark what are you doing?" Mrs. Tanner asked. "Mark it's them. They locked me in here and tried to kill me. They're infected not me. Please Mark, you've known me all your life. Please."

"You sure she's one of them?" Dean asked.

"Yeah." Sam answered.

Dean moved past Mark and shot her.

Dean got a bag of guns and knives from the car and came back. We started going through all of them. We stopped when we heard glass shatter.

"Oh god! Is there any on me? Am I okay?" Pam asked.

"You're clean, you're okay." Dr Lee replied.

"Why are we just standing here? Please, let's just go." Pam said.

"We can't 'cause those things are everywhere." Dean said.

"Oh god. Why is this happening?" Pam asked.

"She's right about one thing. We can't just stay here." I said to Dean and Sam.

" Ally's right. We have to get out of here. To the Roadhouse. Somewhere. Let people know what's happening." Sam said.

"That's a good point. 'Night of the living dead' didn't exactly end pretty." Dean replied.

"I'm not sure if we have a choice. Lot's of people here are good with rifles." Mark said. "Even with all you're hardware, we're easy targets. So unless you've got some explosives..."

"We could make some." Sam said.

Sam grabbed a bottle and we heard knocking on the door.

"Hey! Let me in!" We heard.

"It's Duane Tanner." Mark said before he let him in.

"Oh, thank god." Duane said.

"Duane, you okay?" Mark asked as they walked by us.

"Yeah." He replied.

"That's the guy that I..." Dean started.

"Yeah." Sam answered.

"Who else is in here?" Duane asked.

"Whoa, easy there chief." Dean said. "Hey, doc. Give Duane a good once-over would you?"

"Pam?" Doctor Lee asked.

"Who are you?" Duane asked.

"Nevermind who I am. Doc." Dean said.

"Yeah, okay." She said.

"Duane, where you been?" Mark asked.

"I was on a fishing trip by Roslyn. I came back this afternoon. I saw Roger McGill being dragged out of his house by people we know. They started cutting him with knives. I ran. I've been hiding in the woods ever since. Has anybody seen my mom and dad?" He replied.

"Awkward." Dean commented.

"You're bleeding." Dr. Lee said.

"Where'd you get that?" Dean asked.

"I was running. I must've tripped." Duane said.

"Tie him up. There's rope in there." Dean said.

"Wait-" Duane started.

"Sit down." Dean told him pointing his gun at Duane.

"Sorry Duane. He's right. We've got to be more careful." Mark said.

"Careful? About what?" Duane asked.

"Did they bleed on you?" I asked.

"No. What the hell? No!" Duane exclaimed.

"Doc, any way to know for sure? Any tests?" Sam asked.

"I've studied Beverly's blood test backwards and forwards. It took three hours for the virus to incubate. Sulfur didn't appear in the blood till then. So, no. There would be no way of knowing." Dr. Lee said. "Not until after Duane turns."

"Dean, I have to talk to you. Now." Sam said before they left the room.

"Sit in the chair over there." Mark said.

Duane sat and Mark tied the rope around him so he wouldn't be able to escape.

A few minutes later Dean came in with the gun loaded.

"Where's Sam?" I asked.

Dean ignored me and pointed the gun at Duane.

"Dean. Stop." I said standing in front of Duane.

"Ally. Get out of the way." Dean said.

"No. He might not even be infected." I replied.

"Ally I have no choice." Dean responded.

I walked up to him.

"Don't shoot." I said looking him in the eye.

"Damn it." He said putting the gun down and walking out of the room.

Four hours later: Clinic

Sam, Dean, and I were in one of the rooms putting the explosives together when Dr. Lee came in.

"It's been over four hours. Duane's blood is still clean. I don't think he's infected. I would like to untie him, if that's all right." She said.

After exchanging looks Sam answered.

"Sure. Yeah."

"I'll help." I said leaving the room with Dr. Lee.

I cut the rope with a knife and headed back into the room after healing his leg.

"Where's Sam?" I asked Dean.

We heard a crash and Dean broke the door open and Dean shot Pam in the back. Dean went to go help Sam up but Mark held him back.

"She bled on him." He said. "He's got the virus."

Dean wouldn't let me heal his cut, so we gave Sam an ice pack and took some of his blood.

"Doctor, check his wound again, would you?" Dean asked.

"What does she need to examine him for?" Mark asked." You saw what happened."

"Did her blood actually touch you cut?" I asked Sam.

"Of course it did!" Mark yelled at me.

"We don't know that!" Dean yelled.

"We can't take a chance. You know what we have to do." Mark yelled.

I covered my ears and the lightbulbs broke. Sam grabbed my hand to calm me down.

"Dean, they're right. I'm infected. Give me the gun, I'll do it myself." Sam said.

"Forget it." Dean replied.

"Dean, I'm not gonna become one of those things."

"Sam, we've still got time." Dean replied.

"Time for what?" Mark asked, "I understand he's your brother and I'm sorry. But I've got to take care of this."

Mark pointed the gun at Sam but stopped when we heard pounding on the windows and doors. Mark went to the window in the front of the building and then came back.

"What is it?" Duane asked.

"Just heavy rain." Mark answered.

"But rain wasn't in the forecast. I checked before I left." Duane said.

"Doesn't matter." He said before pointing the gun at Sam again.

"Don't move or else you will be dead before you hit the ground." Dean yelled.

"Then what are we supposed to do!?" Mark yelled.

Dean took out his car keys and gave them to Mark.

"Get the hell away from here. That's what." Dean replied.

"Take my car and the explosives. There's an arsenal in there. You two go with him. You too Ally." Dean said.

"I'm not leaving." I said sitting next to Sam.

"Alright then. Just you two." He said.

"Dean no. This is your chance." Sam said.

"You can't get rid of me that easily." Dean said.

"No, he's right. You should come with us." Mark said.

Dean didn't answer.

"Alright. It's your funeral." He said before leaving with Duane and Dr. Lee.

When the last person left Dean shut the door and locked it.

"I wish I had a deck of cards." Dean said. "Or a foosball table or something."

"Don't do this guys. Just get the hell out of here." Sam said.

"No way." Dean replied,

"Give me my gun and leave." Sam said.

"For the last time Sam. No." I said.

Sam hit the table. "This is the stupidest thing you have ever done."

"I don't know about that." Dean replied.

"I'm sick. And it's over for me. It doesn't have to be for you two. You can keep going." Sam said.

"Who says I want to?" I asked,

"What?" Sam asked.

"I'm tired. Over the years people kept dying for me or because of me. People I cared about just kept dying. Hell, when I was born 20 people died just to keep me alive. Some were old some were as young as five. I just think it's my turn to finally go." I replied.

Dean cleared his throat." I'm going to go get a drink." He said before taking his gun and leaving the room.

"So you're just gonna lay down and die?" Sam asked.

"I tired of people I care about dying, Sam. I never had a dad, I lost my brother, I lost Johnny. An now you." I said standing in front of him.

He pu his hand under my chin and lifted it up until I looked him in the eye.

"I don't want to lose you." I whispered.

Next thing I know Sam crashed our lips together. We stood there for what seemed like minutes until Dean opened the door. We broke apart and I looked at Sam, then backed away.

"Wow, is it hot in here or is it just me?" Dean asked.

I could just feel my face flush red.

"Come on. Doc wants us to see something." Dean said before we left the room.

We walked outside and saw Duane and Mark standing there on the sidewalk. We looked around and saw nothing, no one.

"There's no one. Not anywhere." Dr. Lee said. "They've all just vanished."

We walked back into the clinic and locked the door. Then we went into the room where Dr. Lee was. Sam and I sat on a table while the doctor looked at his blood.

"Well, it's been five hours and your blood's still clean. I don't understand, but I think you dodged a bullet." She said.

"But I was exposed. How could I not be infected?" Sam replied.

"I don't know. You're just not. I mean, when you compare it with the Tanner's samples... what the hell?" She said.

"What?" I asked.

"Their blood. There's no trace of the virus. No sulfur, nothing." Dr. Lee replied.

In the morning Sam, Dean and I were leaning against the Impala while Mark and Duane packed Mark's pick up truck with boxes.

"The Sarge and I are heading south. You should come." Duane told Dr. Lee.

"I better get the authorities up here. If they'll believe me." She replied.

"What about him?" Dean asked motioning to Sam.

"He's gonna be fine. No sign of infection." Dr. Lee said.

Mark and Duane drove off and Dr. Lee went back inside. Dean turned to look at Sam.

"Hey man, don't look at me. I have no clue." Sam said.

"I swear I'm going to lose sleep over this one. I mean why here? Why now? Where the hell did everyone go? It's not like they melted." Dean said.

"Why was I immune?" Sam asked.

"Yeah, you know what? That's a good question." Dean said before getting into the car.

"So. Now I have a question." Sam said moving in front of me.

"Yeah? What's that?" I asked.

"Where does that leave us?" Sam asked.

"That depends. Where do you want us to be?" I asked.

"I want to see where the road takes us." He said before kissing me.

We jumped apart when Dean honked the horn.

I laughed and kissed Sam's cheek before getting into the back seat.