Orochimaru has an eye for the aesthetic.
Thus he has an eye for the degenerate, because degenerate things are beautiful and easy to submit.
Orochimaru has an eye for beautiful, broken things, so of course he has two eyes for Uchiha Sasuke.
The boy is an easy catch. After he gives Sasuke the cursed seal mark he knows he doesn't have long to wait. After he sends the Sound Four he can hardly stand to wait.
Orochimaru can only ever think of himself. It is never a two way deal, it's about shaping Sasuke to Orochimaru's standards, to someone fit to be his mortal shell.
But Sasuke is bound by his ambitions, and thus almost masochistically easy to maneuver.
Orochimaru has an eye for the aesthetic, for the degenerate, the shapeable, so much so that it should be obvious.
But Sasuke has hate, and he is blind.