After the Signer/Dark Signer War, Crystal and her four childhood friends move to Neo Domino City and are preparing for the WRGP. So far, everything is peaceful...or is it? With new enemies and threats appearing, all Signers and their Star Guardians will have to combine their powers to stop them. However, what they don't know was that their tragic futures are about to happen...

At the age of 5, Crystal woke up in a middle of the woods, not knowing who she is nor where she come from. She was then raise in the orphanage and happily grew up with Yusei and his friends. As time passed by, Crystal began to develop mysterious powers and will have to use them to help the Signers save the world, at the same time, recover her memories.