Barry Allen and Caitlin Snow are best friends. They grow up together and fall in love together. Caitlin is forced to leave Central City and Barry. They reunite when fate brings her back to Central City years later. Snowbarry. AU: No Powers

Caitlin's a no-nonsense science major. Barry's the quintessential charming star athlete. When they're paired off and forced to interact in class, Caitlin's determined to resist his charms, but Barry's also pretty determined to get under her skin… It all boils down to a battle between head and heart, and Caitlin's not one to give in to her heart so easily. [College AU]

It's difficult being in love with your best friend, especially when he's oblivious to your feelings and about to propose to someone else. And even though you're happy for him, every day that takes him further away from you, makes it impossible to keep pretending. So you let go, you wish him all the best and leave town in the hopes of saving yourself. *Barry & Caitlin all human AU*