Everything I had done in my life seemed to lead up to this moment. The moment when I found myself bound inextricably to a man I didn’t love, trapped in a life I didn’t want. And if I left him, I would be entirely alone.

Dean and Sam Winchester are sent by Castiel, the angel, to Tree Hill, North Carolina to help a girl named Brooke Davis. Brooke is about to find out that her destiny involves two brothers one who just might be the love of her life and saving the world.