Lloyd Freeman is joined by Amata Almodovar as they leave the safety of the halls of Vault 101 in search of his missing father, stepping into the broken world above. Along their grim path, they encounter harsh adversity and new enemies every step of the way, forge new alliances and meet new friends, and through their actions, they come to change the Capital Wasteland forever.

Even a bullet in the head is not always the end. And those who survive tend to want only two things: answers or revenge. And very often, both.