After discovering that a legendary vampire is searching for an artifact that could grant him absolute power, Damon, Elena, and the rest of the gang from Mystic Falls travel to Beacon Hills, California, in an attempt to find it first. However, they soon realize that Beacon Hills is experiencing its own supernatural problems.

The Winchesters used to make periodic trips to Mystic Falls to check up on the supernatural activity there, but after John's death the trips became forgotten. But now that the business with the Other Side has come to light, the Winchesters have decided to take a long overdue trip to Mystic Falls. Set in S4 of SPN and S5 of TVD.