Piplup, claiming that he was a human, meets up with Chimchar to form Team Poképals. They aspire to become one of the top exploration teams within the Grass Continent, but little do they realize that a greater adventure involving saving the world may be in their prospects. Join them in a grand tale of adventure and friendship! Inspired by the Explorers games and their TV specials.

Mo leaves town for a little while to help her cousin Blythe and Uncle Roger move into their new home of Downtown City. While there, they find out that the new home is an apartment above the pet shop known as Littlest Pet Shop, but unfortunately, the pet shop is in danger of being shut down, so the girls must work together to keep it intact or else it's bye-bye for the pets!

The Fudo family is on their way once again to Alaska, but a flight delayed makes them all feel unfortunate. However, Patch decides to tell the kids the story of his niece Oddball and her first real adventure with the Air Buddies about when they first went to Alaska to pass the time.