A year after the Second battle of Hoover Dam, the NCR, along with the support of the Courier, experienced a industrial revolution; long abandoned factories began to work once more, as blueprints from the Boomers and the BoS were used to increase the arsenal of the New California Republic. On March 15, 2282, the Saderan Empire commited it's first mistake: Don't tread on the Bear.

An unlikely trio get caught in a web of deceit and conspiracy when NCR Chief Hanlon is found dead outside of Camp Golf and General Oliver has seemingly vanished. These three men, a disgraced former NCR medic, an ex-Legionary and a Brotherhood of Steel member imprisoned are brought together and sent out to find the truth for the NCR or face execution at their hands.