"Tell me Peter, do you want to know the greatest pain you can inflict on a man? It's simple, take everything he loves, everything he's fought for...and erase it" Mephisto chuckled darkly at the beaten form of Spider-man lying before him "But what's even funnier is watching him try to regain what he's lost knowing that he'll never accomplish it" Pre-Flashpoint to DC Rebirth

When Metropolis is destroyed by the actions of the Joker and Doctor Octopus, Superman creates the One Earth Regime. As a result Spider-man joins Batman's insurgency while his wife Wonder Woman join's Superman's side. Over the next five years Peter and Diana will be pushed to their limits as they are forced to fight a war that turns allies into enemies and enemies into allies...