After discovering that Cadence is not who she appears to be, Twilight is sent to another world entirely by the disguised Changeling Queen to avoid her plan being disrupted. When Twilight lands, she discovers that not only have Spike and their pets followed her, but that they've arrived in a world where the main sentient species is human. There's still a magic school, though.

"Human" in Equestria fic. Told in 2nd person and featuring "you" as the main character. You are a conduit and you wake up one day to find yourself in an overly colorful world full of small and pastel colored talking horses. This takes place sometime after the "evil" ending of the video game inFAMOUS 2, so spoilers ahead if you haven't played the game yet. (Pre-Alicorn Twilight)