Pīta Pāka, the last living member of the once great Shukeikō-Clan, has to make his own way in a tough ninja world with the amazing abilities gifted to him by his bloodline. He can do anything a spider can, and holding the wise words of his clan's nindō close to his heart, Pīta knows that with great power there must also come great responsibility.

Bitten by a genetically-modified Nephila clavipes (a golden silk orb-weaver spider), boy genius and grade A nerd Peter Parker becomes New York's newest golden orb-weaving, friendly neighbourhood protector, with the help of his friends Daisy Johnson, Harry Osborn and Cindy Moon.