After a biological warfare, humans have extinct and Equestria was born. In the ruins of L.A., there's one human left in the land of Equestria. As the last human, a man named Morgan Neville must survive everyday in his loneliness lifestyle to avoid any danger awaits him. Even if those danger involves magic colorful ponies trying to kill him to erase mankind's mistake from the past.

When a mysterious craft crashes near the Ponyville Lake, Princess Celestia, Luna and 5 of the Mane 6 investigate and find a human near the wreckage. They promptly bring him to the hospital where he awakens frightened & alone. To help him adjust to their world, Applejack volunteers to take 'Cougar' in at her farm. But what happens when the two strike up a very close friendship?