New Marais has been destroyed. A new Beast, more powerful than the first, has launched a war against humanity. The plague that began in Empire City is spreading faster than it can be contained. And the only person who can stop all of it is Cole MacGrath. Now, in Washington D.C., he'll have to raise an army of Conduits to stand against the Beast, and save he world... if he can.

How do you kill the unkillable? How do you break the unbreakable? X-23 and Deadpool find themselves locked in a cell together where it appears they, along with others, are being held in trial for a someone's entertainment value. It doesn't take long to find out who is behind this, and they begin to realize that after all they've been through, they may not survive. (1st in a series)