Peter is on the receiving end of a nasty bite and becomes sick, suffering from a high fever as the toxic bite threatens to take his life. Egon, Winston, Ray and Janine all work together to take care of their dying friend, hoping to help him before it's too late and the devastating injury takes his life. ("Real Ghostbusters" fits the category as well)

The mayor decides to call in professionals to deal with all the ghosts in his city and calls in the Ghostbusters, meanwhile Vlad may have just raised up a new evil unlike he and Danny have ever faced. Crossover with The Real Ghostbusters.