In the years following the outbreak of the cordyceps epidemic, Joel and Tommy's struggle for survival triggers the slow deterioration of their relationship. Follow them through the years as they flee their hometown, drift through quarantine zones, learn brutality and survival on the open road, and eventually find themselves in a city called Boston.

This story bridges the gap between Winter and Spring. Joel witnesses the change that takes place in Ellie after the toll the Winter season takes on her, and does his best to help her deal with it while they press on towards Salt Lake City. The pair encounter obstacles, Infected, hunters, and plenty new experiences along the way. Concludes at the beginning of Spring in the game.