Five years after the events of Danganronpa 3, the world has moved on... Or so we hoped. In the darkness lurked an organization that sought to utilize killing games, not for despair... But for hope. Will these students survive long enough to expose the masterminds behind this and get rescued? Will they want to continue living by the time help arrives?

Hoshido, Nohr, or Revelations? Three young friends debate on which is better, but when they are taken to the land itself, will their will remain strong enough to commit to their side? Can they solve the mystery behind a new malevolent force, or will they be swallowed up in the Outrealm's leaking darkness? As familiar old foes ravage the lands, the world needs a hero...

Eighteen students relocated by Hope's Peak are trapped on a mountain-side resort where they are forced into a horrible killing game. Now they struggle against Monokuma's successor, and perhaps the last member of Ultimate Despair is hiding in their group. Will they unite in friendship to escape together? Or will they all succumb to motives and murder before they can be saved?