I am probably so jumping the gun by putting this up now because this story is nowhere near done...but I want to because why not. Expect slow updates.

Important Notes: If you have not read my other stories that are all a part of a series there are characters that are not explained in this first chapter so here is a brief synopsis.

Sayako- Married Inuyasha and Kagome's son Sota.

Sota- Inuyasha and Kagome's first son

Taisho- Inuyasha and Kagome's second son

Mayumi- Inuyasha and Kagome's second daughter

Izayoi- Inuyasha and Kagome's first daughter

Yuki- Sesshomaru and Rin's daughter

Harutoga- Sesshomaru and Rin's first son

Taiyomaru- Sesshomaru and Rin's second son

Katsumoto- A sentinel, pure-blooded eventually Yuki's lover

At the end of Instinct Sesshomaru collects his nieces knowing that the Well has closed and their parents will not be able to return for ten years.

It will be important to notice which perspective is being used and the chapters will vary in length and only be told from one characters perspective at a time. The plot will go back and forth between past and present...so your brains might hurt but I got my inspiration from My Sister's Keeper by Jodi Picoult. If you haven't read it, you should.

There will also be several parts as the disease runs rampant over a ten year period.

Part One

Inferno

Sesshomaru- Present

His hands shake. The tremors are getting worse. He knows if he does nothing, it's only a matter of months before he will no longer walk the earth. One of the last of his kind, it wasn't an easy pill to swallow.

Today though, they do not shake because of the illness that is taking over his body. Rather they tremble because of the scroll that Taiyomaru brought him from Higurashi shrine. It's almost pathetic that he had never thought to search through the ancient scrolls of Kagome's home for the answer he had been seeking for centuries. He knew it was a monk. He knew the monk was connected to Ungai, whose hatred of yokai was tripled because he was unable to stop Sesshomaru from freeing Rin when she was a little girl. But this, this scroll was the last testament of the monk who laid claim to the slaughter of his kind. For that, and because the well is already closed, Sesshomaru sits in a haze of sweat and confusion at work. Work…if his younger-self knew that he would become a savior of humans, the same humans who slaughtered his people.

"Are you going to read it Oji-sama?" Izayoi asks.

The well has been closed for six months. The girls have been brave over the last half year. Mayumi has finally stopped crying for her father and mother to come back at night. She's thirteen years old. She misses her brothers. She demands to know what happened to Taisho and Sota and her nephew Tatsuo. Because he is not the same demon he was five centuries before, he tells her stories before bed and tucks her in. He kisses the dark haired child's forehead as if she were his own. His lips lay softly where a crescent moon should grace her forehead. Her yoki simply isn't strong enough. One night she draws one on herself with a sharpie and falls asleep in his lap while he reads in his library. She's more human than she is demon.

She attends a local all-girls school in Osaka. She flies with him to his office and meets him there after school. Now she enjoys dive bombing out of the castle in the sky, holding onto his back and waiting for him to pull up. He waits until the last minute, always, until she is screaming so loud she is hoarse and her fingers dig into his shoulders. He used to do it as a dare to see if he could allow himself death. There's too much at stake now.

Izayoi is a different story. She mourned the loss of her father but quickly became interested in the inner workings of her Uncle's home. She learned to care for the many injured and the women who came to give birth. As much as Sesshomaru tries to remind those that have survived not to fight, killing is part of the nature of a yokai. Sometimes the injuries are more than yoki can handle. She was given the same medical skills he passed onto his children, IV's, blood-draws, ultrasounds and isolation measures for when he was forced to bring in those diseased. Thanks to her new skills, she now administers the injections that have been staving off his inevitable death. She's adept at finding his collapsing veins.

Collapsing veins, he can't help but flick his lips as his chin rests in his hands. One such as he, should not have veins that collapse because they are constantly stuck with a cocktail made from the blood of two of his sons and various other components to strengthen his failing nervous system.

When she became bored managing the home, she asked for more responsibility. Now she helps run his clinic in Osaka. She wears a scarf over her head to hide her pointed ears on top of her head and paints her face with make-up to hide the crescent moon on her forehead. She is eighteen now and every bit a young lady.

Sesshomaru worries what he will do in a few more years. She cycles like a human but there is no rush these days to pair her off. She doesn't look like a normal human. Her chosen one will have to come from one of the canine clans. Either one of her own distant cousins or from Shippo or Sayako's people. Reproduction is possible because she is more human than yokai. He thinks she will follow in his footsteps and study medicine. But he doesn't pressure. He knows that teenagers often do the exact opposite of what they are asked simply to spite those around them.

He closes his eyes and tightens his grip on the yellowed parchment. "Perhaps later," he cannot bring himself now to read what is hidden within this document. "Who is my next patient?"

"They canceled," Izayoi sits down on his rather gaudy desk. It's oak and more western than it is Japanese. It's made from a heavy wood that he pretends is impossible for him to pick up just to act as if he is one of the pathetic humans he treats. Everyone thinks he is magnanimous and benevolent for spending his days treating humans. In reality, he chose this specialty to save his own life. There is something familiar and insidious about the leukemic cells that he studies. The way they multiply and destroy system by system so homogenous to the leftovers of the disease that has rent his body.

As much as he yearns for death, to join Rin in the afterlife, there is much left to do before he leaves. He has perfected the cure, but has yet to be able to create a vaccine that would eradicate it completely. Harutoga and Yuki suffer from the same tremors that he does. Jaken and Shippo are near death. He is not ready to see more pure-blooded yokai move on to the afterlife. He is the sole proprietor of the medical knowledge available to the remaining demons in the world. There can be no waiting, if he doesn't act soon, even Yuki's lover will meet the same fate. Katsumoto was once the fastest demon in the world. He now lays in a mess of his own mucous barely able to move. There are so few of them left, he fears what will happen, that this is really the end.

Please review!

If you want this rated M and need your lemons please let me know. I can add those in as well.

And if you are interested in reading a complete original non-fiction by me, check out my wattpad account. There is a link in my profile. It's all about my life with chronic illness for nanowrimo. Look this is me on hiatus. Who the heck am I kidding? LOL