Loki had planned on messing with the hunters extensively once he'd pegged them at the professor's office. It was nothing personal, but he found the fact that they supposedly knew what he was and were supposed to be watching for his tricks made it even more hilarious when they fell for them. Once he'd realized that the two of them were the Winchester brothers, destined to be his older brother's sockpuppets, he'd gone to scope out their motel room in hopes of getting some ideas of the best way to prank them into oblivion. He could use the vicarious payback on Michael and Lucifer.
That particular resolve lasted only until he realized that the cute little brunette changing the diapers of another little Winchester was one of his father's chosen kids.
Most of the other angels wouldn't have known what she was. It was their best defense, after all. An extraordinary spirit hidden in a clay vessel. Even if she should reveal herself in front of most of them, they wouldn't truly understand. The same went for the demons. On both sides, only the truly upper hierarchy would recognize an Instrument, and usually only after they had been declared.
As Gabriel, he'd had more interaction with them than most and knew his Father's Instruments at sight. He'd often been put in charge of them, protecting them and carrying messages to them. This one, though, was new. Gabriel couldn't help but wonder what Father was doing, to allow her to get mixed up with the Winchesters.
Maybe . . .maybe the fight that everyone was winding up to begin wasn't as inevitable as the Host had believed it to be. He should probably search out Father and ask for the truth.
One thing was for certain, he was abandoning this hotbed of pranks immediately. He wanted nothing to do with this mess.