En medio de una misión Skye ve como un hombre es atacado por un caminante y huye. Pasa mucho tiempo sola, buscando a su equipo, hasta que es acogida por un grupo de supervivientes, pero el campamento es atacado y acaban en una prisión muy especial.

After the destruction of the CDC, Agents Fitz and Simmons are called upon to unravel the mystery of the outbreak which has left the dead roaming among the living. Rick doesn't trust anyone, but he will do whatever he has to in order to protect his group. The missions of the two couldn't be more different which may have dire consequences for all. Fitz-centric with others!

In a massive zombie apocalypse, Skye, Ward, Fitz, and Simmons are separated from the team, and soon meet a young girl named Sophia. They all soon meet Carl and Rick Grimes, along with Daryl Dixon and Beth Greene. Soon, the members grow close with each other, only to have their friendships ruined by walkers - and certain secrets. Rated M for violence, language, and sexual content.