I don't own Supernatural or any of it's characters. I only own Isabeau and my own original characters.

Dean is in a dim hallway, grimly turning towards a door and pulling out his gun. He slides out the clip, taps it on the gun, then replaces it.

Isabeau stands beside him, grabbing his arm, "Dean, think about this."

Dean glances at her, saying nothing.

Inside the room, there is a Crater Lake poster on the wall. Below it is a young blond man tied to a chair. Nearby are two women in scrubs, and a tough-looking black man.

The young blonde man looks up as Dean opens the door and enters, raising the gun. Isabeau is right behind him, frowning at the scene before her.

The young man starts babbling desperately, "No, no, no, no, no, you're not gonna... no, I swear! It's not in me!"

"Oh God. We're all gonna die." The younger woman of the two says in fear.

"Maybe he's tellin' the truth." The man says.

Dean advances cocking his gun, "He's not him, not anymore."

"No, stop it! Stop it! Ask her, ask the doctor! It's not in me!" The young man shouts.

"I just . . . I can't tell." The older of the two women shakes her head.

"No, please, don't. Don't. I swear, I-" The younger man cries.

"I got no choice." Dean says, raising his gun.

The young man sobs, "I swear, it's not in me, it's not in me! Don't, don't. Please!"

"Dean!" Isabeau exclaims.

Dean doesn't listen to any of them and fires twice.

Sam, who is lying on the floor beside a motel bed, comes out of his vision.

"Sam. Hey…" Isabeau says crouched down beside him and cupping his cheeks with furrowed brows.

The door opens and Dean enters, chewing on jerky and carrying a six-pack of beer. Isabeau helps Sam up as he's panting.

Dean stops in his place, taking the jerky out of his mouth and looks at Sam, worried, "Sam?" He looks at Isabeau for an answer and she just shrugs, just as worried.

"No…" Sam breathes out.

Dean is driving, Isabeau sits in between him and Sam who is navigating with a GPS device which speaks directions. "Continue on O-R Two-Two-Four West." The GPS speaks.

"There are only two towns in the U.S. named Rivergrove." Sam states.

Isabeau looks over at him, "How come you're so sure it's the one in Oregon?"

Sam has a flashback to the vision; the Oregon poster on the wall, "There was a picture. Crater Lake."

"Okay, what else?" Dean asks.

"I saw a dark room, some people, and a guy tied to a chair." Sam describes.

"And I ventilated him?"

Sam looks over, "Yeah. Isabeau tried to stop you. You thought there was something inside him."

Dean blinks, glancing over, "What, a demon? Was he possessed?"

Sam shakes his head, "I don't know."

Isabeau thinks, "Well, all your visions are always tied to the yellow-eyed demon somehow… So, was there any black smoke? Did we try to exorcise it?" She asks.

"No. Nothing, Dean just plugged him, that's it." Sam answers.

"Well, I'm sure I had a good reason." Dean says.

Sam raises his brows, "I sure hope so."

"What does that mean?" Dean glances over, "I mean, I'm not gonna waste an innocent man." Sam raises his eyebrows again. "I wouldn't!" Dean exclaims.

"I never said you would!" Sam exclaims.

"Fine."

"Fine! Look, we don't know what it is. But whatever it is, that guy in the chair's a part of it. So let's find him, and see what's what." Sam says.

"Fine." Dean answers.

"Fine."

Isabeau stares ahead, rubbing her face. Sometimes her boys were too much.

The three pull into town past a large billboard advertising Crater Lake. They pull up in front of a wooden shop; out front is an older man cleaning a rifle.

Sam notices him and points, "He was there." Sam, Isabeau and Dean get out and approach him.

"Morning." Dean greets.

"Good morning. Can I help you?" The man, Mark, asks.

"Yeah." Dean pulls out his badge, "Uh, Billy Gibbons, Frank Beard and Daniel Mitchell. U.S. Marshals." Sam and Isabeau pull out their own badges.

"What's this about?" Mark asks.

They put their badges away. "We're looking for someone." Isabeau states.

"A young man, early twenties." Sam says, "He'd have a thin scar right below his hairline."

"What'd he do?" Mark asks.

"Well, nothing. We're actually looking for someone else, but we think this young man could help us." Sam explains.

Dean shakes his head, "Yeah, he's not in any kind of trouble or anything; well, not yet." He glances down at Mark's left arm, which shows a distinctive tattoo, "I think maybe you know who he is... Master Sergeant."

Dean smiles, "My dad was in the Corps, he was a Corporal."

Mark smiles, "What company?"

Dean nods, "Echo-2-1."

Isabeau shoves her hands in her pockets, "So can you help us?"

Mark hesitates, "Duane Tanner's got a scar like that. But I know him. Good kid, keeps his nose clean."

"Oh, I'm sure he does. Um. You know where he lives?" Dean asks.

"With his family, up Aspen Way." Mark points in the opposite direction.

"Thank you." Dean says and Isabeau and Sam say their own thank yous'.

They leave and Mark frowns as he watches them go. Across the street, Isabeau bumps into a telephone pole and glances at it in passing. She stops; carved into the wood is a single word: CROATOAN.

They approach the pole and Isabeau points at the word with a significant look, "Hey."

"Croatoan?" Dean questions and Sam's eyes widen.

Isabeau nods, "Yeah."

Dean looks at her and Sam blankly.

Sam huffs, "Roanoke? Lost colony? Ring a bell? Dean, did you pay any attention in history class?"

"Yeah! Shots heard 'round the world, How bills become laws…" Dean trails off.

Sam gives him a look, "That's not school, that's Schoolhouse Rock."

Dean shrugs, "Whatever."

Isabeau sighs, "Roanoke was one of the first English colonies in America, late 1500s?"

Dean remembers, "Oh yeah, yeah, I do remember that. The only thing they left behind was a single word carved in a tree. Croatoan."

Isabeau nods, "Yeah. And I mean, there were theories; Indian raid, disease, but nobody knows what really happened. They were all just gone. I mean, wiped out overnight."

Dean scoffs, and looks at Sam who nods at Isabeau's words, "You don't think that's what's going on here, I mean…"

"Whatever I saw in my head, it sure wasn't good. But what do you think could do that?" Sam asks.

Dean sighs, "Well, I mean, like Isabeau said, all of your weirdo visions are always tied to the yellow-eyed demon somehow, so…"

"We should get help. Bobby, uh, Ellen? Maybe, Bartholmieu and Yvette can help?" Sam asks.

Dean and Isabeau nod. "Yeah, that's a good idea." Dean says and begins walking, Sam and Isabeau follow.

He pulls out his cell phone, then frowns at it, "I don't have a signal." He stops.

Sam and Isabeau do the same, stopping and taking out their phones. Sam shakes his head, "I don't either."

"Three for three." Isabeau comments, frowning at her phone.

They walk to a pay phone, which Dean picks up and dials out the 'out of service' beep. Dean clicks the receiver several times, "Line's dead."

He hangs up, "I'll tell you one thing. If I was gonna massacre a town, that'd be my first step."

The impala is parked outside a cabin, and Sam, Isabeau and Dean approach the front. By the door is a small, tacky plaque that reads 'BORN TO FISH; FORCED TO WORK'.

Sam knocks on the door, and a teenaged boy with dark spiked hair, Jake, opens it, "Yeah?"

Isabeau flashes her badge, "We're looking for Duane Tanner. He lives here, right?"

Jake nods, "Yeah, he's my brother."

"Can we talk to him?" Isabeau asks.

"Oh, he's not here right now."

Dean nods, "Do you know where he is?"

"Yeah, he went on a fishing trip up by Roslyn Lake." Jake says.

"Your parents home?" Sam asks.

"Yeah, they're inside."

"Jake? Who is it?" A man, Mr. Tanner, asks from inside.

Mr. Tanner comes to the door. "Hi, U.S. Marshals, sir, we're looking for your son Duane." Dean says.

"Wh-why? He's not in trouble, is he?" Mr. Tanner asks.

"No, no, no, no. We just need to ask him a couple of routine questions, that's all." Dean says.

"When's he due back from his trip?" Sam asks.

Mr. Tanner winces, "I'm not sure."

"Well, maybe your wife knows." Sam suggests.

Mr. Tanner looks back into the house briefly, "No, I don't know, she's not here right now."

Isabeau tilts her head, "Your son said she was."

"Did I?" Jake asks. Isabeau narrows her eyes at them, something wasn't right here.

Mr. Tanner chuckles, placing a hand on his son's shoulder, "She's getting groceries. So, when Duane gets back, there's a number where he can get a hold of you?"

"Oh no, we'll just check in with you later." Dean smiles.

The three turn and walk down the steps as the Tanners shut the door behind them.

"That was kind of creepy, right? A little too Stepford?" Dean asks.

"Yep." Isabeau agrees.

"Big time." Sam agrees as well.

Looking furtively about, they sneak around to the back of the house, crouching below a window.

Inside the Tanner house, the mother, Beverly Tanner is tied to a chair and gagged. Jake comes around behind her, hands on her shoulders, "It's okay, Mom. It's not gonna hurt."

Mr. Tanner comes out of the next room with a kitchen knife. Jake stands in front of his mother and casually rolls up one sleeve, his father cuts into his arm and lets the blood drip onto a wound in Beverly's shoulder.

Outside, Sam, Isabeau and Dean arm themselves and Dean kicks down the back door. As they rush in, handguns raised, Mr. Tanner rushes at them with a knife.

"Put it down!" Sam shouts as Isabeau and Dean both shoot Mr. Tanner in the chest.

Jake jumps out the window, shattering glass, and darts off into the woods. Sam aims at him through the window but hesitates, giving him time to get away.

Beverly is in the back seat of the impala with Isabeau. They pull up in front of the clinic and Isabeau helps Beverly out and leads her to the door with Sam. Dean opens the trunk and looks around.

The two lead Beverly inside; the clinic is quiet, dim, and empty. "Hello? Hello? We need a doctor here!" Sam calls out

A young woman, Pam, rushes out, concerned, "Mrs. Tanner, what happened?"

"She's been attacked." Isabeau says.

"Doctor Lee?" Pam calls out.

Dr. Lee rushes in, "Bring her in."

"Okay." Sam says as he and Isabeau guide Beverly.

Pam leads them into a back room, and Dr. Lee follows. Dean enters, carrying the canvas-covered body of Mr. Tanner hoisted over his shoulder, "Hey."

Dr. Lee turns to him, "Is that-"

"Mr. Tanner?" Dean finishes.

"Was he attacked too?" Dr. Lee asks.

"Uh . . . no, actually, he did the attacking and then he got himself shot." Dean tells her.

"Shot?"

"Yeah."

"And who are you?" Dr. Lee asks.

"U.S. Marshal. I'd show you my badge, but uh…" Dean indicates Mr. Tanner's body.

Dr. Lee nods, "Oh, Sorry. Bring him back here."

Beverly is seated on a stool with her shoulder exposed. Dr. Lee sits across from her, treating the wound on her left shoulder, "Wait, you said Jake helped him? Your son Jake?" Dr. Lee asks.

Beverly nods, "They beat me. Tied me up."

"I don't believe it." Pam says, standing off to the side.

"Pam." Dr. Lee holds a hand up to her, "Beverly . . . do you have any idea why they would act this way? Any history of chemical dependency?" She asks Beverly.

"No, of course not. I don't know why. One minute they were my husband and my son. And the next, they had the devil in them." Beverly explains.

Sam, Isabeau and Dean are listening to this, and they share a look at her last words. "We gotta talk." Dean tells Isabeau and Sam.

They exit the lab and into another room. "Those guys were whacked out of their gourds." Dean says.

"What do you think? Multiple demons, mass possession?" Sam asks.

Dean shrugs, "If it is a possession there could be more. I mean, God knows how many, it could be like a friggin' Shriner convention."

Sam sighs, "Great."

Dean nods, "Of course, that's one way to wipe out a town, you take it from the inside."

Isabeau shakes her head, "I don't know. We didn't see any of the demon smoke with Mr. Tanner, or any of the other usual signs."

"Well, whatever. Something turned him into a monster." Dean says and turns to Sam, "And you know if you woulda taken out the other one there'd be one less to worry about."

"I'm sorry, all right? I hesitated, Dean, it was a kid!" Sam says, annoyed.

Dean shakes his head, "No, it was an 'it'. Not the best time for a bleeding heart, Sam." Dean says.

Isabeau shakes her head at him, shoving her hands into her pockets.

Dr. Lee stalks out of the lab, her heels clicking loudly on the floor.

"How's the patient?" Isabeau asks.

"Terrible! What the hell happened out there?" Dr. Lee asks.

Dean shakes his head, "We don't know."

"Yeah? Well, you just killed my next door neighbor."

"We didn't have a choice." Dean defends.

Dr. Lee nods, "Maybe so, but we need the county Sheriff. I need the coroner…"

"Phones are down." Sam says.

"I know, I tried. Tell me you have a police radio in the car?" Dr. Lee asks.

"Yeah we do. But it crapped out just like everything else."

Dr. Lee huffs, "I don't understand what is happening."

Dean asks, "How far is it to the next town?"

"It's about forty miles down to Sidewinder." She answers.

"All right, I'm gonna go down there, see if I can find some help." Dean claps Sam and Isabeau on their shoulders, "My partners will stick around, keep you guys safe." Dean starts to walk out.

"Safe from what?" Dr. Lee asks.

Dean looks back at them, "We'll get back to you on that."

Sam is leaning against a counter, staring at the body of Mr. Tanner. Isabeau herself is standing next to Mr. Tanner's body, staring down at him.

Sam pushes off the counter to stand next to Isabeau, his hand sliding underneath the back of her shirt, and caressing her skin.

Isabeau leans into his side with a sigh, her hand moving to the very same thing to Sam.

Dr. Lee is nearby, looking at something in a microscope, "Huh."

"What?" Sam asks as he and Isabeau look over.

Dr. Lee looks away from the microscope, "His lymphocyte percentage is pretty high. His body was fighting off a viral infection."

"Really?" Isabeau asks, "What kind of virus?"

Dr. Lee shakes her head, "Can't say for sure."

"Do you think an infection could have made him act like that?" Sam asks.

"None that I've ever heard of. I mean, some can cause dementia, but not that kind of violence. And besides, I've never heard of one that did this to the blood." Dr. Lee says.

"Did what?"

"There's this . . . weird residue. If I didn't know better I'd say it was sulfur." Dr. Lee answers.

Isabeau glances down at Mr. Tanner's body, "Sulfur." She looks up at Sam who seems just as worried as she is.

Sam and Isabeau are staring intently at Beverly, still huddled on the stool in the lab. "I don't understand. Are you saying my husband and Jake had a disease?" Beverly asks.

Dr. Lee nods, "That's what we're trying to find out. Now, during the attack, do you remember… did you have any direct contact with their blood?"

"Oh my God. You don't think I've got this virus, do you?" Beverly asks.

"Beverly, I don't know what to think. But with your permission, we'll take a blood sample." Dr. Lee says.

Beverly nods and lays her hand gently on Dr. Lee's. Suddenly she grabs Dr. Lee's wrist and yells in rage, lashing out with her other hand.

Isabeau's eyes widened while Sam advances on her and she tosses him against a glass cabinet, which shatters.

She picks up a scalpel and she advances on him, still yelling.

Isabeau picks up a fire extinguisher and comes up behind Beverly, swinging it at her head, knocking her out. Isabeau pants staring down at Beverly's unconscious form, "You good, Stretch?" She asks Sam.

Sam chuckles, "Yeah. I'm good, Beau. Thanks."

Isabeau shrugs, "No problem."

Dr. Lee is again looking through the microscope while Pam huddles against the far wall, "What if we all have it? What if we all go crazy?" She asks, panicked.

Dr. Lee looks over at her, "You've got to stay calm. All we can do is wait. The Marshal's bringing help."

Isabeau and Sam look over, listening to the conversation.

"I can't, I… I've got to go." Pam moves to leave the room.

"Pam!"

Pam turns to them, "No, you don't understand. My boyfriend's out there, I gotta make sure he's okay."

She hurries out of the lab, and Sam and Isabeau follow her all the way to the lobby.

"All right, wait, wait. Please. Look, I know you're upset, all right? But it's safer if you stay here for now. Help is coming." Sam explains.

The impala pulls up outside. Isabeau points to the outside, "There they are."

"Sammy? Beau? Open up!" Dean shouts from outside.

Sam and Isabeau go to open the door to let in Dean and Mark; both are still armed.

"Did you guys, uh, get to a phone?" Sam asks, closing the door and locking it.

"Road block." Dean tells them. "I'm gonna have a word. Doc's inside." He tells Mark and Mark heads in.

"What's going on out there, Dean?" Isabeau asks.

Dean shakes his head, "Sweetheart, I don't know, I feel like Chuck Heston in the Omega Man, I mean, Sarge is the only sane person I could find. What are we dealing with, do you know?"

Isabeau nods, "Yeah. Doc thinks it's a virus."

Dean nods, "Okay, great. What do you two think?"

Sam and Isabeau exchange a look. "We think she's right." Sam says.

"Really?" Dean asks.

"Yeah. And we think the infected are trying to infect others with blood-to-blood contact. Oh, but it gets better. The uh, the virus? Leaves traces of sulfur in the blood." Sam explains.

"A demonic virus?"

"Yeah, more like demonic germ warfare. At least it explains why I've been having visions." Sam says.

"It's like a Biblical plague." Dean comments.

Isabeau nods, pulling out her grimoire, the one that once belonged to her father and starts flipping through it, "Yeah. You don't know how right you are, Dean. We've been poring through my Dad's grimoire and found something about the Roanoke colony."

"And?" Dean asks her.

Isabeau sighs, "Where is it? Ah! Dad always had a theory about Croatoan. He thought it was a demon's name. Sometimes known as Daeva or sometimes Resheph. A demon of plague and pestilence." She explains.

Dean shakes his head, "Well, that, that's terrific. Why here, why now?"

Isabeau shuts her grimoire, putting back inside her jacket while Sam speaks, "I have no idea. But Dean, who knows how far this thing can spread? We gotta get out of here, we gotta warn people."

"They've got one! In here!" Mark shouts.

The three enter the main waiting room where Mark is. "What do you mean?" Dean asks.

"The wife. She's infected." Sam tells him.

"We've gotta take care of this. We can't just leave her in there. My neighbors, they were strong. The longer we wait, the stronger she'll get." Mark says.

Dean barely hesitates before pulling out his gun and stalking into the lab.

"You're gonna kill Beverly Tanner?" Pam asks with everyone now in the lab.

"Doctor, could there be any treatment? Some kind of cure for this?" Sam asks. Dr. Lee flustered, doesn't answer.

"Can you cure it?" Dean asks.

"For God's sake, I don't even know what 'it' is!" Dr. Lee exclaims.

"I told you, it's just a matter of time before she breaks through." Mark adds in.

"Just leave her in there, you can't shoot her like an animal!" Pam exclaims.

"Sam. Isabeau." Dean says.

They go to the door of the utility room, where Beverly is being held. Dean and Mark hold their guns ready while Sam carefully opens the door, holding Isabeau behind him with one arm. Isabeau gives Sam a look for that.

Dean and Mark take up offensive positions. Inside, Beverly is huddled on the floor, knees drawn up. She jumps at their approach, "Mark, what are you doing? Mark, it's, it's them! They locked me in here, they, they tried to kill me! They're infected, not me! Please, Mark! You've known me all your life! Please!"

"You sure she's one of 'em?" Dean asks Sam and Isabeau.

Sam nods, his face twisted in distress. Isabeau nods as well, frowning, "Yeah."

As Mark pulls back, near tears, Dean steps forward and fires twice.