On September 20th of 1963, John F Kennedy proposed a joint Soviet-US Moon mission. In our timeline, Kennedy was assassinated before Premier Khrushchev could respond. In this timeline, Lee Harvey Oswald fails and Khrushchev accepts Kennedy's proposal. See how one different decision changes the following events. (I'm not good at summaries)

The 1st Exploration fleet under Admiral James Anderson enters Gargantua to explore a new world and stumbles upon the Mass effect Universe. How will the Citadel species react to another humanity that freely uses AI and Dragon lookalikes with access to the Shroud? Only time will tell.

Four hundred years have passed and the galaxy is prospering. Commander John Shepard has become the galaxy's most favoured hero and most if not all sentient beings strive follow in his examples. For Amanda W. Shepard, she has to live up to her ancestor's legacy and lead by example, top of her academic and military classes, she is stressed out. Things are about to get more stressful.