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Good Guys
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Crash: A cool bandicoot ready to save the world – again
Coco: Crash's sister who tags along

Crunch: Crunch was Cortex's weapon to destroy Crash in Crash Bandicoot 4: The Wrath of Cortex
But (spoilers, if you haven't finished the game) at the end Crash found out Crunch was being controlled by Cortex with a remote control, so Crash destroyed the remote control and Crunch turned good.

Dinosaur from Crash Bandicoot 3: Crash found this little dino in one of the prehistoric levels. He helped Crash get a secret gem. Crash and the dino are great friends.

Pura the Tiger: Pura is Coco's friend she found it in the 'Great Wall of China' level, it helped her get the crystal in that level, as well as the gem.

Aku Aku: Uka Uka's good twin, he helps Crash in his quests by being a shield against attacks directed to Crash.

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Bad Guys turned into good guys...for the moment

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Neo Cortex: Neo Cortex (N.Cortex for short) always wanted to conquer the world and turn the human race into his slaves with the help of the Cortex Vortex. Crash ruined his plans for world domination...four times in a row. The fourth and final time (spoilers) Cortex's space station exploded and he, his minions (except N.Trophy, that went missing in his time machine) and Uka Uka landed in the south pole. After months
creating a new plan to destroy Crash and his friends, Cortex realized that he will never conquer the world. After three months they arrived at a jungle, and after seven months in the jungle eating beetles and wumpa fruits a weird beam transported a video from a space station to the earth. Cortex caught it, and thanks to a creation of one of Cortex minions (N.Gin) they were able to watch the video...what a bad day. After three days walking and escaping from tigers, Cortex and his minions found Crash's house... and so the adventure begins....

Tiny The Tiger(or Taz Tiger from Crash 2): Tiny (who isn't really tiny) is a big and bad tiger, one of Cortex's strongest minions.

Dingodile: Dingodile is another of Cortex's experiments. He is half dingo and half crocodile, armed with a flamethrower.

Other of Cortex minions

N.Gin: Half man, half machine, with a missile stuck in his head, a genius that can create anything.

Uka Uka: Aku Aku's evil twin, Neo Cortex's boss. He wants to conquer the world and destroy his good brother, but now he must join the side of good and help to beat the evil N.Tropy.

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Really Bad guys!

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N.Tropy: The evil mastermind. He is the master of the evil side of time!

Crusher: He's armed with a bazooka. He is like Crash, but he has Crunch's muscles and Crash's little brown hair.

W.Rartex: He was Cortex's rival in school.

Tricky Trucka: he is the *very evil* twin brother of Uka Uka and Aku Aku.He wants to destroy the entire galaxy!

N.Rin: N.Gin's rival in school

Big the Rex: He is a big bad T-rex!

Dogeel: Half dog, half eel!

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The really evil mastermind!!
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¿?: Im not gonna spoil this big and very evil enemy. I'm only gonna say that he can turn good people into bad people, thanks to his hypnotism!

Hint: He appears in one of the Crash games for GBA! Go and buy the game and you will know who it is....