Yooka and Laylee decide to visit their old home, Crittertown, while they run into Ms. Bun-Bun, Vya-Lynn, and Crunch Time. But while they were adventuring in their old home, Captial B and Dr. Quack captured the Crittertown World book to burn Yooka-Laylee alive. But luckily, their friends in Tome Island are trying to stall the two villains so the heroic duo can return.

Before their adventures, Yooka and Laylee stayed at a city called Crittertown while living in an orphanage, Foster Home for Critters. They were cared for by the owner; Ms. Candy Bun-Bun, made a childhood bully in Crash "Crunch Time" Crocodile and made rivals in their counterparts; Vya-Lynn. But how did they met, and how did they find Shipwreck Creek?

Dr. Quack sends a mercenary to spy on Yooka and Laylee, and find out where they hid the powerful book that V.I.L.E. wishes to get their hands on. But upon meeting the odd couple, the spy realizes that Yooka may be getting under her skin.

Yooka and Laylee accept Trowzer's quest for a lost gemstone and go on their way. Remembering directions is not easy. And things quickly drop downhill.

Yooka-Laylee Poem: A psychotic bat being carried around by a silent chameleon. Eh, there's been stranger combinations.

Yooka and Laylee always had fun playing and adventuring together, working as a team. It's what they did; what they always did. Though this time their adventure seemed to run cold when they get caught amidst a raging blizzard. With her friend falling unconscious, its up to Laylee to get him-and herself-to safety.