Alex Karev. He knew he had lost Izzie to Denny a long time ago. But, yet when he died suddenly due to his heart condition, Alex was there for her. It tore his heart in tiny pieces to have seen her cuddled up next to her love. Yet, no one had gotten through to Izzie except the very one whose heart she had broken.

He gently wrapped his arms around her and carried her into his arms, away from Denny. She needed that. She needed someone to have comforted her who knew how it felt to have lost someone he loved. He had clung on to Izzie as she hung on to him for support. He held on to her and gently rocked her in his arms slowly. She cried on his shoulder. Alex was the one person she leaned on in her time of sorrow.

Alex painfully embraced her tightly while she cried. And he cried along with her inside his broken heart.

Dr. Alex Karev is so in love with her. He never stopped loving Izzie.. Tonight was the night he finally realized how much he loved her.

"Goodbye, Denny." Izzie cried.