Nono has been patiently levelling up her bond with "Ichirou", and good news is, All for One is rusty in his people-reading-skills/Nono taught Kabuto all he knows, so All for One is beginning to trust her, which means that she starts coming in contact with Shigaraki.
Also, she sneaks samples from the full-body reconstruction to her beloved lab partner. Organization resources mean genetic sequencing in addition to extraordinarily vast databases, so they get an idea of what quirks All for One has.
No, Oro, additional data is not a reason to start experimenting with bloodline transfers. That is Bad, we talked about this, do we need to revise empathy and ethics again?
Sensei has been given Sensei's seal of approval, so Shigaraki is naturally well-inclined towards her, even if she is that double-classing assassin's mother. Bad decision on AfO's part, given that simply being sociable, reasonable, and somewhat affirmative while providing actual human contact makes Tomura Very Attached.
Probably medical shenanigans. There's definitely a whole lot of senpais telling their kouhais that while Orochimaru-sensei disregards lab protocol, you should not. Don't follow sensei's example with using lab equipment as cookware! Especially not used lab equipment!
Nono's aggressive at least six hours of sleep, preferably eight a day policy for her ducklings, morning runs and healthy eating and all the other examples of don't burn yourself out.
Then we have Nono and Kurogiri tag-teaming Tomura, introducing regular baths and skin lotion and halfway decent parenting. Nono broaches the subject of Kurogiri/Cadaalada's past.
Enter Quirk under control!Aamusnaan. Heartfelt reunion, the proof that what All for One promised-help for his son and all others with difficult to manage quirks, justice in the world, peace to war-torn lands-could be achieved, and it was done by someone else instead. Naturally, his loyalties begin to sway.
The Sports Festival gives Oto publicity, followed by exponential growth.
Of course, an extremely aggressive reinterpretation of some rather poorly written legally binding documents mean that, as far as the Yakushis are concerned, teaching their students to use their quirks in tandem is perfectly legal and a reasonable extension of "use all means at their disposal to ensure the health and safety of those under their care".
Hosu goes as expected from their side.
Maybe a furious mutter of just how many prayers were "please give my child/me a good quirk".
Enter Chisaki Kai. Dabi manages to sneak out tissue samples from Eri, and they find that her quirk desn't work on non-humans, see Buko, Nedzu, and Manda.
Orochimaru has to be restrained from devising some manner of biological weapon: If they wish to see pestilence, then I shall give them one, dearest, let go of me, this is a perfectly reasonable reaction.
In the mean time, Aamusnaan and Cadaalada have wonderful father-son reconciliation and bonding experiences, the league of villains get stuck doing interesting things like helping old ladies across the streets and renovating old buildings and helping people live lives of reasonable quality.
Nono asks All for One for use of his forces to deal with Chisaki Kai, in exchange for a reduction in medical fees. He thinks it is a wonderful idea that reinforces her allegiance to him, she finds it a wonderful way to subvert his subordinates.
Assault on the Yakuza is helped along by Cassandra's terrifying ability to bring confusion to any situation, Dabi's kill it with fire, and the League of Villains having an acceptable target without worries of police/hero interference (the Organization is good for a lot of things).
Manda the teleporting trauma blanket for evacuating Eri.
Then we have Nono calling Chisaki a disgrace to science. Choice quotes I've scribbled down include:
Correlation does not equate causation. You conflate symptoms with cause. Such idiocy is beyond even children. Truly your mask is well made, for you bear upon your face the mark of foolishness, that would burn victims and breath herbs in your delusions about plagues. When questioned about the reasonability of using quirks illegally, Nono answers: I am licensed. A license to utilize any and all means at my disposal to ensure the health and safety of my patients.I believe that the license was issued under the assumption that it was merely a directive to utilize my quirk in the operating room, but given that aid is best given in a timely fashion, and that an ounce of prevention is better than a pound of cure, my purpose would not be ill-served in being present on the battlefields. Then, it is only reasonable that I ensure the health and safety of my potential patients my neutralizing those who would cause them injury. Hence I clearly have permission to preemptively end threats to your potential wellbeing.
Toga bonds with Dabi, because some things are just meant to be. Twice has been getting mental help from Oto, so he isn't really inclined to join the LoV.
Finally, the even more bare-bones resolution, in which Orochimaru possesses All for One, Nono is even more exasperated than usual, and Otogakure's mandate is reiterated.
LoV gets enfolded into Otogakure as its martial branch, and all's well that ends well.