Isaac Campbell had seen many strange things in his life. He had been apprenticed to his uncle to learn the trade of a Hunter at the age of twelve. During the hours when most people tucked themselves away in bed next to a warm fire, he was out running under the moonlight, chasing the demons away. Isaac had seen a man grow fur under the light of a full moon. He had seen a shifter change its face as easily as a snake sloughing its skin. He had been a Hunter twenty years now, and Isaac Campbell had seen all there was to see. He didn't expect the New World to offer any surprises.

Yet here they were, not even off of the ship, and two strangers claimed that they had walked through a door from the future to meet with their ancestors.

Men of Letters. Isaac's uncle had warned him about the scholars who liked to poke their noses where they didn't belong, and drag trouble back in their wake. Men of Letters didn't care who lived and who died. They were like curious children, always exploring, never cleaning up their own mess.

Isaac's uncle had partnered with Men of Letters once. It had gotten him killed.

Isaac leveled his best glare at the two strangers, the one that made even the most seasoned soldiers squirm. "Why would men from the future come here? This ship is full of sick people. Winter is coming, and we haven't even found a place to land, much less begun to build. There will not be enough food to go around. This is not a good place to be."

"Yeah, well, this isn't where we meant to be!" The shorter brother, Dean, replied. "The spell didn't work right, so if you'll get out of the way, we'll just go home!"

"Wait!" Sam placed a hand on his brother's shoulder. "Dean, I know I did that spell right. We came here for a reason, and I would like to figure out what it is."

"We are on a ship full of Pilgrims! Running around asking people if they know about a type of gun that hasn't been invented yet is not a good plan!"

"Do you want to fix the Colt or not?"

"Fix a young horse?" Anne asked. She had her head tilted to one side, watching the brothers through narrowed eyes. "I am confused. There are no horses on board."

Sam opened his mouth to explain, but the cabin door burst open again. A young man staggered across the threshold. Isaace recognized him as Thomas, the younger brother of the woman who had escorted him to this cabin at gunpoint.

Thomas' clothes were disheveled, his hat knocked askew. He clutched his shoulder, but blood squirted between his fingers. His face was pale and his knees shaky. Isaac frowned, recognizing the symptoms. Judging by the amount of blood dripping down his harm, the kid had mere minutes before he bled out past the point of no return.

"Anne!" Thomas' eyes lit on his sister, and she dropped her pistol to free her hands to catch him. Isaac recognized the fear in her eyes. He had seen that expression too many times in his life. This woman held her entire world in her arms, and knew that she might only have minutes before she lost the thing she loved the most.

"Thomas. Oh, Thomas, what did you do!"

"I found the vampire, Anne! You said I couldn't, but-"

"I said you shouldn't! Thomas Winchester, so help me if you die-"

But Anne did not have time to say more. The strangers from the future were in motion. One had gathered Thomas in his arms and guided him to the bed while the other began to pull supplies out of their bag. They were strange tools that Isaac did not recognize, but he knew that now was not the time to ask questions. He watched, silent as a fly on the wall, while the brothers worked in tandem, there movements coordinated as only a team who have worked together for decades can be.

The had announced themselves as members of the Winchester family, but they acted like a team of Hunters than Men of Letters. They cleaned and stitched the wound as if they had done this a hundred times before.

Isaac stepped closer to get a look at the wound. A bite mark. A vampire bit.

Hm.

"He's lost too much blood," Dean said. He was the shorter of the two, but Isaac guessed that he was the older brother. The lines around his eyes were deeper, and he took charge in a way that said he was used to taking the lead.

"Did we bring the saline kit?" If Sam was the younger brother, he was no less competent. Thomas had barely flinched as Sam stitched him up. As the men moved about, Isaac caught a glimpse of weapons tucked into their belts and more tucked into their bags.

There Winchesters were definitely not Men of Letters.

"We brought everything. There ain't no way one of us is dying in the old west, or on the Mayflower, just because they didn't know how to do medicine yet." Dean produced a set of tubes, one short and thick, full of clear water, the other long and flexible, and tipped with a needle. He carefully turned Thomas' arm toward him and aimed the needle directly at the space where the elbow bent.

"Stop!" Anne had stood by quietly through the entire ordeal, but now she stepped forward and grabbed Dean's hand before he could puncture her brother's skin. "What are you doing? He has lost too much blood! Bleeding him will not help!"

Dean grimaced, but he didn't shake Anne off or dismiss her as some Hunters might. Instead, he held up the needle to she could get a better look. "I'm not going to bleed him. See this? I'm going to put some fluid in him to help with the blood loss."

Isaac's stomach did a somersault at the idea, and Anne's face turned green. "Put it in him?"

"It's ok!" Sam moved from his position next to Thomas and wrapped a comforting arm around Anne while Dean carefully pushed the needle into Thomas' skin. "It's a sterile saline solution. It, um—it will help his body until he can make more blood. We've done it before, I promise it won't hurt him."

Isaac winced. 'I promise' were two words a Hunter should never say. There was no way to guarantee a life would be saved or a foe vanquished. Still, he hoped the young man would be alright. One hundred and fifty years ago, people thought that there was nothing beyond the great ocean, yet here they were, ready to build homes on the other side of that ocean. Perhaps, in one hundred and fifty years, these men from the future had learned how to put blood back in a person. Stranger things could happen.

Most importantly, perhaps Thomas could name his attacker and Isaac would be able to finish this hunt.