Leah, Lorraine- Kari Wahlgren
Kaylin, Katelyn, Zara, Miley- Kimberly Brooks
Rylie- Catherine Taber
Tania, Isla - Kate Micucci
Paige and Tang- Stephanie Sheh
Estrella, Sumiko, Aaron, Olive, Dr. Japon, Pineapple, Marisol- Grey Griffin
Kirby- Makiko Ohmoto
Swinger, Mr. Downs- Frank Welker
Billie, Betty- Nicole Sullivan
Grandma Clarice - Bonnie Hunt
Grandpa Wendell- Bruce Campbell
Fayth and Leelannee- Cree Summer
Uncle Rusty, Vernon- Phil LaMarr
Otto, Bobby- John DiMaggio
Cristina, Carolina, Charlotte- Nika Futterman
Chief Hess, Ricardo, Rudolph, Harry Rowe- Tom Kenny
Hyobe- James Sie
Peter- Steven Yeun
Aranea, Koharu and Kristi- Tara Strong
Mayor Hess- Christine Ebersole
Mrs. Hess, Wadha- Jennifer Hale
Principal Hopkins- Jill Talley
Isaac, Mufit- Scott Menville
Martin- Dave Wittenberg
Helen- Ashley Eckstein
Norma Jean- Alexandra Shipp
Quin Quincey- Jane Lynch
Saffron Foreman- Vanessa Hudgens
Dr. Avienus- Kevin McDonald
Mr. Carnevale- Danny DeVito
Zahra Carnevale- Lucy DeVito
Clark McBruce- Richard Brancatisano
Wayne McBruce- Josh Gad
Keiynan- Keiynan Lonsdale
Montana Marley- John Tui
Jimena Downs- Demi Lovato
Alessandra- Rita Moreno
Lucca McDaniel- David Tennant
Maurice McDaniel- Craig Ferguson
Eli- Neil Patrick Harris
Azalea Faulkner- Kathy Najimy
Mila Caradonna- Chrissie Fit
Adeline Ewart- Grace Phipps
Nayeli- Toks Olagundoye
Christian Benbow- Josh Peck
Atticus Harmon- Mark Hamill
Nathaniel Harmon- Ryan Gosling
Brynlee Winterbottom- Betty White
Additional Voices: Grey Griffin, Cree Summer, Dee Bradley Baker, Collin Dean, Alan Tudyk, Tom Kenny, Jill, Talley, Lara Jill Miller, Jessica DiCicco, Kerry Williams, Kayzie Rogers, Ted Lewis, Eric Stuart, Eden Sher, Adam McArthur, Candi Milo, Eric Bauza, Catherine Tate, Keone Young, James Sie