Kryptonite is a mystery and, as such, it should be shrouded in fog. A murky threat to Superman. One rarely seen or used. Unfortunately, the current Superman and Lois TV show turned into a kryptonite of the week series almost immediately after it premiered. I stopped watching the show after its first season for several reasons including this. Happily, I own DVDs of the Superboy TV series. 100 episodes with kryptonite featured in less than a dozen of those eps. The series created new and novel threats for Superboy which made for engaging stories unlike Superman and Lois which uses kryptonite as a crutch and effectively takes all the mystery away.
