News about the poison
Suddenly , Greg opened his eyes and , looking at Catherine , he tried to tell her something , but he felt like throwing up . Catherine noticed and called for help .
The doctor came in to take a closer look to Greg . He look worried , so he called some nurses to help him stabilize the patient .
Catherine and Sara were kicked out of the room ; they went to Sara's room where they started to talk .
"So , what do you think ?I heard the poison was very toxic ; Nick told me so ."
"I know ; some of the components are lethal ; there was arsenic , thallium even some snake venom."
"Snake venom ?! Oh my God ….do you know what type of snakes ?"
"He told me only about vipers . Is good , because this has an antidote and there were other ten poisons . But … I don't know if arsenic has one … "
"Hope it has … I really hope so !"
"Why are they getting him in the ICU ?" Catherine asked , looking through the window .
…
Greg was admitted to the ICU for hemodynamic monitoring. He had sinus tachycardia, with heart rates ranging from 130 to 180 beats per minute .
He demonstrated no hypotension or arrhythmias. He received intravenous fluids at twice the maintenance rate and standard chelation therapy with BAL through intramuscular injection every half an hour .
While in the ICU, his QTc prolonged to as long as 527 milliseconds , decreasing to 450 milliseconds without specific therapy.
His electrocardiographic results remained normal for the remainder of his hospital course.
Greg was transitioned to oral chelation therapy with 2,3-dimercaptosuccinic acid , and BAL administration was continued , along with D-penicillamine . .
The doctor went out of the ICU and taking the mask off , he entered the room Catherine and Sara were in .
"What happened , doctor ?"
"He had some sort of renal failure ; we took our chances and gave him some BAL and D-penicillamine - a combination that will slow the effect of the poisoning "
"What is that ?"
"Dimercaprol or BAL is the first-line agent available in for treating arsenic poisoning and D-penicillamine for thallium poisoning "
"Is it bad ?"
" Look, once arsenic- the worse oh these two - distributes into the tissues, treatment may be unsuccessful. Clinical trials are not available for us, but attempting to remove arsenic from the plasma before it reaches the tissues made sense. Because the clearance of arsenic by dialysis is substantial, hemodialysis may be indicated if available in a short time after"
"Oh my Lord…"
"And he also had shown signs of thallium poisoning and we gave him D-penicillamine ,that was evaluated in rats as treatments against acute thallotoxicosis. Is good thing exists … "
"But … how this stuff reacted with the others chemicals in his system ?"
"Well , I understand that you haven't analyze his blood , so we did it . The only substances we found in his system is this combination of thallium and arsenic."
"What ?"
"Only two poisons ."
Catherine breathed relieved and took Sara's hand in hers .
"Well , he suffered Acute exposures to arsenic , that is generally manifest with the choleralike gastrointestinal symptoms of vomiting ,often times bloody and severe diarrhea which may be often bloody too ; he will experience acute distress, dehydration and hypovolemic shock. When you called me he was just having a shock ."
"But , if there are only two things in his blood , you can't just create a cure ? only using those two…"
"No ,miss , because we don't know what concentration was used in the first place ; with the doses we gave him , we only slowed , not stopped the effect …"
"Only slowed ? he has more time to live ?" Catherine interrupted .
" …. But the sure thing is that he has the same time to live … only twenty three hours . We only stabilized him , we couldn't get that stuff out of his system "the doctor continued , with this answering to her question "The trivalent forms or arsenic are more toxic and react with thiol groups, while the pentavalent forms are less toxic but uncouple oxidative phosphorylation. . And he wasn't so lucky to receive a pentavalent one …Very few organ systems escape the toxic effects of arsenic. "
"Okay doctor ." Sara said ."and when can we see him ?"
"In an hour , after I'm done . And the bad news is that now I can't give him any painkiller , because they'll react to the BAL and produce an cardiac arrest ."
"So , a last question : is better to stay awake in pain than asleep ? I don't really understand why is there an improvement . He has the same time to live , but in pain….can you explain ?" Sara asked .
"Yeah . Before , those 23 hours were the best … it wasn't sure . I couldn't say he had that much . Now he does . And another thing : then , if you found the cure in the last hour , probably his body wouldn't react to it ; now it will until he's dead . Understand ?"
"So , he has better chances to survive ?"
"Oh yeah ."
The doctor left .
"So , this must be good news ? That he lied to us ?" Sara asked .
"Well , there are still bad news … but why to give us his blood with so many chemicals ? And why the hell we didn't check his blood after we found him ?"
"I think I know the answer ." Sara told her "you see , if we worked with the blood he gave us , maybe we were developing a cure that killed him… he would make us all feel guilty for his death .this was his purpose . "
"You're right …how could we be so idiots ?"
Catherine took out her cell phone and dialed Grissom's number .
"Hey Cath !"
"Hey Gil ."
"Everything okay ?"
"News ."
"What news ?"
"Hodges lied to us ."
"What ?"
"Remember , he gave us the blood , Greg's blood with those poisons , right ? " Catherine tried to stay calm .
"Yeah…"
"That was a lie , a big one ! In Greg's system are only two substances : thallium and arsenic . Nothing more .Nothing less ."
"This is good ?"
"It may be ; we only need to find out what concentrations were used .But he has still 23 hours to live "
"So , why the hell Hodges lied ?"
"Think a little … we create a cure , an antidote for thirteen different poisons and in his system are only two of those….got it ?"
"So , that bastard wanted to make us kill Greg ? I can't believe this . " Grissom asked , dazed .
"Greg had a seizure , he started throwing up and the doctor told me this stuff after he checked him .By the way , where are you guys ?"
" On the way to the house . We have a few minutes . So I understand that his blood can't give them what they need , huh ?"
"No"
"Okay then . I'll go with the guys . Be careful and keep him fighting , okay "Grissom said to her , before she hung up .
….
Here is chapter 25 ! Sorry if there are too many technical terms … I wanted to sound that there is no hope left…. Am I bad ? maybe , you'll never know .
Please review !
