The doctor came in fifteen minutes later. It was 9:15 at night, way past Brianna's bedtime, but due to her little nap, she was wide awake.

"Hey everyone. I have some news for you. Because it is so late, we are letting you go home for the night. We will start chemo tomorrow. You're appointment time is 12:30, is that feasible?" The doctor asked.

Madison nodded her head.

"Ok, when your home, take it easy. Get a lot of rest, because chemotherapy will be very trying."

Again Madison nodded.

"We'll see you tomorrow."

---------------------------------------------------

Dean checked out and pulled the Impala around to meet Madison. Brianna sat in the back and she sat up front with Dean.

The ride home was silent, both trying to deal with the tremendous weight that had been dropped on their shoulders. Turning around to make sure Brianna was asleep, she turned to face Dean.

"How you doing Dean?" She asked quietly; know this had really shaken her brothers.

Dean snorted, "You are just diagnosed with cancer and you're asking me how I feel."

Dean shook his head and kept looking out the wind-shield.

"Talk to me Dean," she said quietly.

Tears filled his eyes, "It's not fair…" he whispered.

Madison nodded his head in agreement.

"Why couldn't someone just cut us a break…" he whispered, hitting the steering wheel with his hands.

"I don't know. But we'll fight this, I'll do everything I can to stay longer with all of you."

"You don't know what's gonna happen, Madison. Don't say your gonna…" Dean couldn't even say the words.

"Dean, it's in my lungs. And if the doctor said it spread…I'm not giving up by any means, but we've got to…prepare ourselves for the worse case scenario."

"No we don't," Dean answered stubbornly.

"I do Dean. I've got a little girl that I need to make sure will be ok," Madison felt the tears well up.

"It's not going to get that far," Dean said stoically.

"What do you mean?"

Dean said nothing, but continued to stare out the window.

"Dean I know what you're thinking. But do not look for some supernatural way to stop this. It's not a demon curse or a possession. I have cancer, Dean, cancer. Promise me you will not go looking for any explanation or cure for what happened. Look how well it turned out last time you and Sam did,"

Dean remained silent.

"Dean, promise me. Please," Madison reached over and grabbed his hand.

"I promise," Dean whispered.

The remaining car ride home was spent in silence. They arrived at Madison's house, Dean carried Brianna and Sam helped Madison.

On Madison's request, they put Brianna in her king sized bed, next to her. The boys, deciding they couldn't be anywhere else, slept there two and they all climbed into the bed; Dean, Brianna, Madison and Sam, the boys on the outside of course.

Tomorrow would be the start of chemotherapy.

--------------------------------------

Madison and Dean arrived at the hospital at 12:20. Madison decided Brianna should stay home, she didn't want her daughter to see her like this.

They sat in the waiting room with the other patients. Young and old individuals with various states of health sat among them. It scared Madison to death; this was to be her future. Dean, seeing her fear, squeezed her hand in encouragement. Ten minutes later, they called her in.

Madison sat on the bed at the end of the room, among all the others receiving chemo. Dean pulled a chair up next to the bed, waiting for the inevitable. The nurses bustled around, preparing the medications and equipment. A young nurse came over to Dean and Madison with a smile on her face.

"Hey Madison, I'm Alyssa and I'm gonna be administering your chemotherapy today. The doctor will be by shortly to explain more about the medications. I'm just the messenger."

Alyssa gently grasped Madison's wrist in order to start a I.V, and Madison couldn't help but to pull away.

"Hey, it's ok. When you feel you're ready, shout for me ok?" Alyssa gave her a kind smile, and went to check on her other patients.

Madison liked her, she was almost the same age as her. She understood how terrified she was. Dean was thinking the same thing, adding how smoking hot she was.

Dr. Peterson made his way over to Madison and Dean.

"Hey guys," he said pulling a chair up to the bed. "We got the results from the test that determines where the cancer has unfortuneately spread. I'm sorry, but we have found some in your stomach and in some of your lymph nodes."

Madison put her head in her hands, wondering if chemo was even worth it. She was dying, and by the sounds of it, very soon.

"Umm…what will I get…out of taking the chemo?" she asked breathlessly.

"More time with your family is all I can guarantee. I'm sorry," He hated delivering this news; how devastated people always looked.

Madison nodded and said nothing. She silently wiped her eyes and felt Dean gently took Madison's hand into his.

Alyssa had prepared all the medications for her patient, but after Dr. Peterson had left them, they looked like they needed a few minutes.

Alyssa pushed her cart up to Madison's bed and handed her a tissue. She actually sat at the foot of her bed and looked at Madison.

"Hey, are you ready to get started?" she asked. Madison nodded and grabbed Dean's hand as if it was her only lifeline.

"Ok, first I am going to insert the I.V, ok?" Madison nodded, staring at the ceiling, holding her breath as the nurse quickly found a good vein.

"Great, that went well. Ok, so here's the deal. There are numerous drugs that combine to be a effective force to fight your cancer. Your chemo will be for everyday for the next month. After that, we see how things go. We are giving you a high dosage, so we have to see how that affects your cancer ok?"

Madison nodded.

"Today will be your longest day, we like to call it your jump start day. The first drug I'm gonna administer might give you a tingling sensation in your fingers, toes, nose, lips. If that occurs, I can dilute it. Ready?"

Madison strangely trusted her and nodded yes. Alyssa pushed the first drug through and within minutes, Madison's eyes filled with water at the burning sensation running through her body.

"Oh God," she whispered, making Dean grasp her hand harder. "I…I can't feel my fingers," she whispered trying not to panic.

"Ok, I'll dilute the medication. Is that better?" She regained at little bit of feeling, but not all.

Around a hour into the process, Madison had fallen asleep. Alyssa came back to check on the medicine when Dean decided to strike up a conversation.

"So, why did you decide to work in a place like this?"

Alyssa smiled, "You know, everyone asked me that. My little brother, he uh, passed away at 17 from cancer. I know first had how hard it is to watch a sibling be sick. The nurses with my brother were…old and just threw out the facts. I want to give families hope, even if there isn't any."

Dean nodded, appreciating her honesty. He was gonna keep the conversation when he heard Madison groan. Immediately his attention shifted and he was standing by his sister.

"Mad, you ok?" he asked, but she didn't answer, just moaned again and began moving her head back and forth slowly. Dean saw her start to gag and before he could even react, Alyssa had a basin under his sisters' mouth. Madison didn't even open her eyes but wretched terribly, but with little strength. Dean was looking terrified by his sister's sudden sickness and Alyssa saw his concern.

"Hey, it's ok. Sometimes people become disoriented during chemo. It will wear off as we wean down the drugs." Madison by this time stopped throwing up and Alyssa wiped her chin.

"I'll be back with the last round so you two can hit the road."

"Thanks," Dean answered sincerely. He appreciated her kindness, it made the situation a little more bearable.

Dean's focus returned to his sister and saw her eyes bat.

"Hey ladybug. You ok?"

Madison groaned and searched for Dean's hand. Dean reached for hers and brought it close to him.

"This sucks Dean," Madison whimpered.

"I know, kiddo, I know."

Three hours from the start, Dean wheeled his weakened sister out to the Impala to make the trip home.